Vitamin E and Allergic Contact Dermatitis
2010; Lippincott Williams & Wilkins; Volume: 21; Issue: 3 Linguagem: Inglês
10.2310/6620.2010.09083
ISSN2162-5220
AutoresPayman Kosari, Ali Alikhan, Mary Sockolov, Steven R. Feldman,
Tópico(s)Retinoids in leukemia and cellular processes
ResumoReports of vitamin E-induced allergic contact dermatitis (ACD) and frequent use of vitamin-E derivatives (tocopherol, tocopheryl linoleate, tocopherol acetate, etc) in skin care products deserves further investigation into tolerability and suitability of vitamin E in skin care preparations. A PubMed search was conducted to review the prevalence of vitamin E-induced ACD. It revealed 931 cases of vitamin E-induced ACD mainly from one large study. There were no reported deaths and only three patients required hospitalization for treatment. It appears that vitamin E-induced ACD is an uncommon phenomenon; incidence is low despite its widespread use in skin care products. Given its antioxidant and photoprotective properties, vitamin E should remain an ingredient in skin care products.
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