Type 1 wild poliovirus and putative enterovirus 109 in an outbreak of acute flaccid paralysis in Congo, October-November 2010
2010; European Centre for Disease Prevention and Control; Volume: 15; Issue: 47 Linguagem: Inglês
10.2807/ese.15.47.19723-en
ISSN1560-7917
AutoresGilda Grard, Jan Felix Drexler, Sonia Etenna Lekana-Douki, M Caron, Alexander N. Lukashev, Dieudonné Nkoghe, Jean‐Paul Gonzalez, Christian Drosten, Eric M. Leroy,
Tópico(s)Whipple's Disease and Interleukins
ResumoAn outbreak of flaccid paralysis syndrome in adults is ongoing in Congo. Molecular analysis of faecal, throat and cerebrospinal samples identified wildtype 1 poliovirus and an additional enterovirus C strain related to enterovirus 109 as the cause. As of 22 November, the cumulative number of cases was 409, of which 169 (41.3%) were fatal. This is one of the largest wild type 1 poliovirus outbreaks ever described associated with an unusually high case fatality rate.
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