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Hemochromatosis Terminating in Polycythemia and Hepatoma, with Observations on the Natural History of Hemochromatosis

1963; Massachusetts Medical Society; Volume: 269; Issue: 20 Linguagem: Inglês

10.1056/nejm196311142692002

1533-4406

James H. Jandl, Charles S. Davidson, Walter H. Abelmann, Richard A. MacDonald,

Liver Disease Diagnosis and Treatment

LIVER tumors, usually hepatomas, are relatively frequent in cases of hepatic cirrhosis, occurring in approximately 3 or 4 per cent of patients with alcoholic cirrhosis and in a somewhat higher percentage (approximately 6 to 14 per cent) of those with postnecrotic cirrhosis or hemochromatosis.1 , 2 Polycythemia is encountered in association with tumors of a number of tissues, including the liver.3 4 5 6 7 The present report concerns a patient with hemochromatosis who was followed for several years, and in whom, during the last few months of life, a fulminant polycythemia and cancer of the liver developed simultaneously.Case ReportThe patient was 58 years . . .