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Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities

2016; Multidisciplinary Digital Publishing Institute; Volume: 21; Issue: 4 Linguagem: Inglês

10.3390/molecules21040493

1433-1373

Jiangkun Dai, Na Li, Junru Wang, Uwe Schneider,

Phytochemistry and Bioactivity Studies

In this review, more than 60 natural canthin-6-one alkaloids and their structures are considered. The biosynthesis, efficient and classic synthetic approaches, and biological activities of canthin-6-one alkaloids, from 1952 to 2015, are discussed. From an analysis of their structural properties and an investigation of the literature, possible future trends for canthin-6-one alkaloids are proposed. The information reported will be helpful in future research on canthin-6-one alkaloids.