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Child-Pugh, MELD, and ALBI scores for predicting the in-hospital mortality in cirrhotic patients with acute-on-chronic liver failure

2016; Taylor & Francis; Linguagem: Inglês

10.1080/17474124.2016.1177788

1747-4132

Ying Peng, Xingshun Qi, Shanhong Tang, Han Deng, Jing Li, Ning Zheng, Junna Dai, Feifei Hou, Jiancheng Zhao, Ran Wang, Xiaozhong Guo,

Hepatitis Viruses Studies and Epidemiology

Our study aimed to evaluate the discriminative abilities of Child-Pugh, model for end-stage liver disease (MELD), and albumin-bilirubin (ALBI) scores in predicting the in-hospital mortality in cirrhotic patients with acute-on-chronic liver failure (ACLF).Cirrhotic patients with ACLF admitted between 2010 January and 2014 June were retrospectively reviewed. Areas under the receiver operating characteristic curves (AUROCs) with 95% confidence intervals (CIs) were calculated.One hundred patients were eligible for the Asia-Pacific Association for the Study of the Liver (APASL) criteria. AUROCs of Child-Pugh, MELD, and ALBI scores in predicting the in-hospital mortality was 0.63 (95%CI: 0.52-0.72, P = 0.05), 0.75 (95%CI: 0.65-0.83, P < 0.0001), and 0.53 (95%CI: 0.42-0.63, P = 0.69), respectively. Eighty-eight patients were eligible for the EASL/AASLD criteria. AUROCs of Child-Pugh, MELD, and ALBI scores in predicting the in-hospital mortality were 0.59 (95%CI: 0.48-0.69, P = 0.14), 0.57 (95%CI: 0.46-0.68, P = 0.26), and 0.57 (95%CI: 0.46-0.67, P = 0.29), respectively. There was no significant difference among them.Child-Pugh, MELD, and ALBI scores might be ineffective in predicting the in-hospital mortality of cirrhosis with ACLF.