Portal de Periódicos da CAPES

Application areas of 3D bioprinting

2016; Elsevier BV; Volume: 21; Issue: 8 Linguagem: Inglês

10.1016/j.drudis.2016.04.006

1878-5832

İbrahim T. Özbolat, Weijie Peng, Veli Özbolat,

Additive Manufacturing and 3D Printing Technologies

Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.