Spinal Cord Hamartomatous Myelodysplasia in 2 Horses With Clinical Neurologic Deficits
2016; SAGE Publishing; Volume: 53; Issue: 4 Linguagem: Inglês
10.1177/0300985815622971
ISSN1544-2217
AutoresKyle R. Taylor, Robert J. MacKay, Elizabeth A. Nelson, A. L. Stieler, John F. Roberts, William L. Castleman,
Tópico(s)Veterinary Orthopedics and Neurology
ResumoTwo horses euthanized for neurologic deficits were diagnosed with hamartomatous myelodysplasia of the spinal cord. One was a 5-week-old Holsteiner colt exhibiting spasms of muscle rigidity in the extensor muscles of the limbs and epaxial muscles, and the other was a 3-year-old Thoroughbred colt exhibiting progressive ataxia and hypermetria in the pelvic limbs. Each had focal disorganization of the white and gray matter of the spinal cord forming a mass interspersed with neurons, glial cells, and disoriented axon bundles. In the Holsteiner colt, the mass was at the level of C 5 and included islands of meningeal tissue contiguous with the leptomeninges. The mass occluded the central canal forming hydromyelia cranial to the occlusion. In the Thoroughbred colt, the mass was at the level of L 1 on the dorsal periphery of the spinal cord and did not involve the central canal.
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