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Short sleep duration increases salivary IL-6 production

2016; Taylor & Francis; Volume: 33; Issue: 6 Linguagem: Inglês

10.3109/07420528.2016.1167710

1525-6073

Érica Lui Reinhardt, Pedro Augusto Carlos Magno Fernandes, Regina P. Markus, Frida Marina Fischer,

Circadian rhythm and melatonin

Morning shift sleep restriction has been associated with higher plasma IL-6 levels. The aim of this study was to investigate the effect of sleep duration on salivary IL-6. Sleep duration of morning shift workers was estimated by actigraphy. Workers with "longer sleep duration" (LSD; N = 6) and "shorter sleep duration" (SSD; N = 15) were then compared regarding salivary IL-6 levels determined at 14:00 h, bed and wake times. SSD workers did not show daily variation of IL-6 and presented higher levels at bedtime and 14:00 h compared to LSD workers. In this study, SSD is associated with an increase in salivary IL-6 content.