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Changes in respiratory function in Pembroke Welsh Corgi dogs with degenerative myelopathy

2016; Japanese Society of Veterinary Science; Volume: 78; Issue: 8 Linguagem: Inglês

10.1292/jvms.15-0521

1347-7439

Kanae OYAKE, Yui Kobatake, Sanae SHIBATA, Hiroki Sakai, Miyoko Saito, Osamu Yamato, Kazuya Kushida, Sadatoshi Maeda, Hiroaki Kamishina,

Veterinary Orthopedics and Neurology

Canine degenerative myelopathy (DM) is characterized by progressive degeneration of the spinal cord. Although atrophic changes in the intercostal muscles were previously reported in the late stage of DM in Pembroke Welsh Corgis (PWCs), changes in respiratory function have not yet been examined. In the present study, we performed an arterial blood gas analysis and measured respiratory movements over progressive disease stages to document changes in respiratory function in DM-affected PWCs. We found that respiratory dysfunction progressed during the later stages of DM and correlated with a change in respiratory movement to the abdominal breathing pattern. These results suggested that hypoventilation occurred due to dysfunctional changes in the intercostal muscles and resulted in hypoxemia in the later stages of DM.