ADDITIONAL PROOF OF REDUCTION OF ETHANOL ABSORPTION FROM RAT INTESTINE <italic>IN VIVO</italic> BY HIGH ACETALDEHYDE CONCENTRATIONS
1995; Oxford University Press; Linguagem: Inglês
10.1093/oxfordjournals.alcalc.a045752
ISSN1464-3502
AutoresHiroshi Kinoshita, Iwao Ijiri, Setsuko Ameno, Chiaki Fuke, Kiyoshi Ameno,
Tópico(s)Biochemical effects in animals
ResumoWe investigated intestinal ethanol absorption in rats pretreated with saline, cyanamide, 4-methylpyrazole and cyanamide + 4-methylpyrazole. The value of the absorption rate constant in the cyanamide-pretreated group with high acetaldehyde levels was the lowest among the four groups, but there were no significant differences among the remaining groups. We found that high acetaldehyde concentration itself clearly reduces intestinal ethanol absorption.
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