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BIBTEX RIS

Anti- Pseudomonas aeruginosa activity of 1,10-phenanthroline-based drugs against both planktonic- and biofilm-growing cells

2015; Oxford University Press; Volume: 71; Issue: 1 Linguagem: Inglês

10.1093/jac/dkv292

ISSN

1460-2091

Autores

Lívia Viganor, Anna Clara Milesi Galdino, Ana Paula Ferreira Nunes, Kátia Regina Netto dos Santos, Marta H. Branquinha, Michael Devereux, Andrew Kellett, Malachy McCann, André Luis Souza dos Santos,

Tópico(s)

Antimicrobial agents and applications

Resumo

ObjectivesThe beneficial antimicrobial properties of 1,10-phenanthroline (phen)-based drugs, together with the imperative need to develop new chemotherapeutic options for prevention/treatment of infections caused by MDR Gram-negative bacteria, led us to evaluate the effects of phen, 1,10-phenanthroline-5,6-dione (phendione), [Ag(phendione)2]ClO4 and [Cu(phendione)3](ClO4)2·4H2O on planktonic- and biofilm-growing Pseudomonas aeruginosa.

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