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A Short-Term Clinical Evaluation of L-697,661, a Non-Nucleoside Inhibitor of HIV-1 Reverse Transcriptase

1993; Massachusetts Medical Society; Volume: 329; Issue: 15 Linguagem: Inglês

10.1056/nejm199310073291502

1533-4406

Michael S. Saag, Emilio A. Emini, Oscar L. Laskin, Jeffrey A. Douglas, William I. Lapidus, William A. Schleif, Richard J. Whitley, CAROL S. HILDEBRAND, V W Byrnes, John C. Kappes, Kevin W. Anderson, F Massari, George M. Shaw,

HIV/AIDS Research and Interventions

The non-nucleoside reverse transcriptase inhibitors are novel antiretroviral agents with selective activity in vitro against human immunodeficiency virus type 1 (HIV-1). They act through direct inhibition of reverse transcriptase and are not incorporated into DNA.