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First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina

2016; Lippincott Williams & Wilkins; Volume: 47; Issue: 6 Linguagem: Inglês

10.1161/strokeaha.116.013637

1524-4628

M. Cecilia Bahit, Mariano Coppola, Patricia M. Riccio, Lauren E. Cipriano, Gregory A. Roth, Renato D. Lópes, Valery L. Feigin, Brenda Borrego Guerrero, Maximiliano De Martino, Alejandro Díaz, Daniel Ferrante, Fernando Funaro, Pablo M. Lavados, M. Laura Lewin, Daniel H. López, Patricia Macarrone, Rafael Marciello, Diego Marmorato Marino, Cecilia Martens, Paula Felippe Martinez, Guillermo Odriozola, Alejandro A. Rabinstein, Gustavo Saposnik, Damián Silva, Ramón Suasnabar, Thomas Truelsen, Araceli Uzcudun, Carlos Viviani, Luciano A. Sposato,

Blood Pressure and Hypertension Studies

Background and Purpose— Epidemiological data about stroke are scarce in low- and middle-income Latin-American countries. We investigated annual incidence of first-ever stroke and transient ischemic attack (TIA) and 30-day case-fatality rates in a population-based setting in Tandil, Argentina. Methods— We prospectively identified all first-ever stroke and TIA cases from overlapping sources between January 5, 2013, and April 30, 2015, in Tandil, Argentina. We calculated crude and standardized incidence rates. We estimated 30-day case-fatality rates. Results— We identified 334 first-ever strokes and 108 TIAs. Age-standardized incidence rate per 100 000 for Segi’s World population was 76.5 (95% confidence interval [CI], 67.8–85.9) for first-ever stroke and 25.1 (95% CI, 20.2–30.7) for first-ever TIA, 56.1 (95% CI, 48.8–64.2) for ischemic stroke, 13.5 (95% CI, 9.9–17.9) for intracerebral hemorrhage, and 4.9 (95% CI, 2.7–8.1) for subarachnoid hemorrhage. Stroke incidence was slightly higher for men (87.8; 95% CI, 74.6–102.6) than for women (73.2; 95% CI, 61.7–86.1) when standardized for the Argentinean population. Thirty-day case-fatality rate was 14.7% (95% CI, 10.8–19.5) for ischemic stroke, 24.1% (95% CI, 14.2–36.6) for intracerebral hemorrhage, and 1.9% (95% CI, 0.4–5.8) for TIA. Conclusions— This study provides the first prospective population-based stroke and TIA incidence and case-fatality estimate in Argentina. First-ever stroke incidence was lower than that reported in previous Latin-American studies, but first-ever TIA incidence was higher. Thirty-day case-fatality rates were similar to those of other population-based Latin-American studies.