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Validation of PI‐RADS v.2 for prostate cancer diagnosis with MRI at 3T using an external phased‐array coil

2016; Wiley; Volume: 44; Issue: 5 Linguagem: Inglês

10.1002/jmri.25284

1522-2586

Matteo Baldisserotto, Eurico J. Dornelles Neto, Gustavo Franco Carvalhal, Aloyso F. de Toledo, Clovis M. de Almeida, Carlos Eurico Dornelles Cairoli, Daniel O. de Silva, Eduardo Carvalhal, Ricardo Paganin, A Agra, Francisco de Souza Santos, Jorge Antônio Pastro Noronha,

Prostate Cancer Treatment and Research

Purpose To date, few studies have validated the Prostate Imaging Reporting and Data System Version 2 (PI‐RADS v. 2) for the diagnosis of prostate cancer. Our aim was to validate PI‐RADS v.2 using 3 Tesla (T) MRI. Materials and Methods This is a retrospective study of 54 consecutive patients who underwent 3T MRI with a body‐array coil for diagnostic confirmation of prostate cancer or cancer staging between June 2013 and June 2015. Sensitivity, specificity, and agreement were calculated based on a criterion of PI‐RADS score = 3. Inter‐examiner agreement was determined by the weighted kappa statistic. Results Histological findings were positive for cancer in 33 patients and negative in 21 patients. Considering a PI‐RADS score of 3 as positive for cancer, the accuracy of each reader was 85.20% and 70.40%, respectively, and agreement coefficients were κ = 0.69 and κ = 0.35. Considering PI‐RADS 3 as absence of cancer, the accuracy of each reader was 77.80% and 77.80%, respectively, and agreement was κ = 0.55 and κ = 0.54. Inter‐reader agreement was moderate/good (weighted κ = 0.53; 95% confidence interval: 0.39–0.66; P = 0.038). Conclusion High accuracy was obtained for the diagnosis of prostate cancer using 3T MRI with a body coil and the PI‐RADS v.2 score. J. Magn. Reson. Imaging 2016;44:1354–1359.