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BIBTEX RIS

Simulation of in vitro digestion coupled to gastric and intestinal transport models to estimate absorption of anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits

2016; Elsevier BV; Volume: 24; Linguagem: Inglês

10.1016/j.jff.2016.04.021

2214-9414

Fernanda Marques Peixoto, Iva Fernandes, Ana Cristina Miranda Senna Gouvêa, Manuela Cristina Pessanha de Araújo Santiago, Renata Galhardo Borguini, Nuno Mateus, Víctor de Freitas, R. L. O. Godoy, Isabel M. P. L. V. O. Ferreira,

Polysaccharides Composition and Applications

The bioaccessibility of the anthocyanins from peel powder of jabuticaba, jamelão and jambo fruits under gastro-intestinal conditions and their gastric and intestinal absorption was examined in order to estimate anthocyanin transport efficiency (ATE). Thus, in vitro digestion coupled to epithelium absorptive models (gastric MKN-28 and intestinal Caco-2) was applied independently for each phase. The bioaccessibility of anthocyanins after gastric digestion were 13% for jabuticaba, 45% for jambo and 65% for jamelão, whereas intestinal bioaccessibility were 10% for jabuticaba, 15% for jambo and 45% for jamelão. The assays showed that, applying the MKN-28 cell model, the ATE were 19.7, 9.7 and 14.1%, respectively, for jambo, jabuticaba, and jamelão powders, whereas using the Caco-2 cell model these results were 0.8, 0.2 and 0.3%, respectively. In conclusion gastric mucosa plays an important role in anthocyanin's absorption.