Altered Activity of the Sodium-Potassium Pump in Arteries of Rats with Steroid Hypertension

1978; Portland Press; Volume: 55; Issue: s4 Linguagem: Inglês

10.1042/cs055041s

ISSN

0144-4107

Autores

Motilal B. Pamnani, David Clough, Francis J. Haddy,

Tópico(s)

Ion Transport and Channel Regulation

Resumo

1. Ouabain-sensitive uptake of 86Rb, a measure of the Na+—K+ pump activity, was studied in tail arteries of rats made hypertensive with deoxycorticosterone and saline. 2. Decreased activity of the ouabain-sensitive Na+—K+ pump supports the hypothesis that the activity of Na+—K+ pump is suppressed in volume-expanded hypertension.

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