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How common is heart failure? Evidence from PACT (Prescribing Analysis and Cost) data in Nottingham

1995; Oxford University Press; Linguagem: Inglês

10.1093/oxfordjournals.pubmed.a043163

1741-3850

Katy Clarke, David Gray, J R Hampton,

Pharmaceutical Practices and Patient Outcomes

The aim of the study was to determine the prevalence of heart failure in Nottinghamshire by an analysis of prescriptions for loop diuretics. An observational study was carried out in the Nottingham Health District, on the basis of Prescribing Analysis and Cost (PACT) data relating to nearly 400000 kg of frusemide prescribed in the year 1991–1992 and general practitioner (G P) records on two groups of patients (total 903)prescribed frusemide. The total amount of frusemide prescribed on a daily basis in Nottinghamshire is 1 048566 mg. The mean daily dose of frusemide per patient is 60 mg and the median dose 40 mg. There are between 13107 and 26214 patients taking frusemide in Nottinghamshire. Fifty-six per cent of patients prescribed loop diuretics by their GP fulfil diagnostic criteria for heart failure. The prevalence of heart failure in Nottinghamshire estimated from loop diuretic prescribing increases from 0·1 per cent in the age-group 30–39 years to 5·45 per cent in patients aged over 90 years.