Produção Nacional
Revisado por pares
Low-Level Laser Therapy (780 nm) on VEGF Modulation at Partially Injured Achilles Tendon
2016; Mary Ann Liebert, Inc.; Volume: 34; Issue: 8 Linguagem: Inglês
10.1089/pho.2016.4092
ISSN1557-8550
AutoresJulio Fernandes de Jesus, Diva Denelle Spadacci-Morena, Nayra Deise dos Anjos Rabelo, Carlos Eduardo Pinfildi, Thiago Yukio Fukuda, Hélio Plapler,
Tópico(s)Bee Products Chemical Analysis
ResumoThe aim of this study was to analyze the modulatory effects of near infrared (780 nm) low-level laser therapy (LLLT) on the presence of the vascular endothelial growth factor (VEGF) in the partially injured Achilles tendons of rats.LLLT stimulates the healing process for Achilles tendon injuries, although the extent of the modulatory effect of LLLT on the VEGF levels found in the injured tendons remains unclear.Sixty-five male Wistar rats were distributed in the following seven groups: LASER 1, 3, and 7 (10 partially injured Achilles tendons in each group, which were treated with LLLT for 1, 3, and 7 days, respectively); Sham 1, 3, and 7 (same injury, with simulated LLLT); Control group containing the five remaining animals and in which no procedures were performed. LLLT was applied once a day for 10 sec, with a mean power of 70 mW and fluency of 17.5 J/cm(2). After euthanasia, all of the Achilles tendons were surgically removed and the VEGF levels were analyzed using immunohistochemistry.The VEGF levels remained close to normal (p > 0.05) when comparing the experimental groups (LASER and Sham: 1, 3, and 7) with the Control group.LLLT did not stimulate the expression of VEGF in the treated Achilles tendons.
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