EFFECTS OF CHRONIC EXCESS SALT INGESTION
1962; Rockefeller University Press; Volume: 115; Issue: 6 Linguagem: Inglês
10.1084/jem.115.6.1173
ISSN1540-9538
AutoresLewis K. Dahl, M. Heine, Lorraine Tassinari,
Tópico(s)Nutrition, Genetics, and Disease
ResumoUsing the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.
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