Polycythemia Vera with Ph1 Chromosomes in Two Brothers
1967; Elsevier BV; Volume: 30; Issue: 4 Linguagem: Inglês
10.1182/blood.v30.4.503.503
ISSN1528-0020
AutoresWilliam C. Levin, Elsie W. Houston, Stephan E. Ritzmann,
Tópico(s)Acute Myeloid Leukemia Research
ResumoAbstract Two brothers with polycythemia rubra vera have been studied: one before treatment and one after many years of treatment. Direct harvests of marrow aspirates from both patients exhibited the presence of the Ph1 chromosome. Moderately increased LAP levels were present in both. Available data do not indicate whether the disease and the chromosomal aberrations in these two brothers are familial or fortuitous.
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