Hemoperfusion with a New Anion Exchange Resin Corrects the Metabolic Alkalosis in Pyloric Stenosis: An Experimental Demonstration
1992; SAGE Publishing; Volume: 15; Issue: 11 Linguagem: Inglês
10.1177/039139889201501111
ISSN1724-6040
AutoresStefano Faenza, Marco Balestri, Giovanni Martinelli, M Spighi, Milena Fini, Roberto Giardino, L. Colì, Giuseppe Cianciolo, S. Stefoni, V. Bonomini,
Tópico(s)Electrolyte and hormonal disorders
ResumoAn experimental model of hypertrophic pyloric stenosis was made by suture of the pyloric wall and gastrostomy in 10 rabbits under general anesthesia. Blood sampling indicated severe alkalosis and hypochloremia 3h 30 min after surgery. To correct the derangement, we tested an ion exchange resin (Dowex SAR), coated with a methacrylic hydrogel. A cartridge containing 18 g of this resin was inserted in an extracorporeal circuit. This chloride charged resin achieved uptake of HCO − 3 ions, and elution of CI − ions. The electrolytic balance was fully restored after 10 min of treatment.
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