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Nephrotic Syndrome During Treatment with Alpha-Mercaptopropionylglycine

1979; Lippincott Williams & Wilkins; Volume: 122; Issue: 3 Linguagem: Inglês

10.1016/s0022-5347(17)56420-4

1527-3792

Gianfranco Rizzoni, Luigi Pavanello, Noemi Dussini, Lino Chiandetti, Graziella Zacchello,

Porphyrin Metabolism and Disorders

No AccessJournal of UrologyCase Reports1 Sep 1979Nephrotic Syndrome During Treatment with Alpha-Mercaptopropionylglycine G. Rizzoni, L. Pavanello, N. Dussini, L. Chiandetti, and G. Zacchello G. RizzoniG. Rizzoni , L. PavanelloL. Pavanello , N. DussiniN. Dussini , L. ChiandettiL. Chiandetti , and G. ZacchelloG. Zacchello View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)56420-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail We report 2 cases of cystinuria in which, a nephrotic syndrome developed during treatment with alpha-mercaptopropionylglycine. This syndrome resolved after withdrawal of the drug and it did not recur when the alpha-mercaptopropionylglycine was given again in lower doses. The hypothesis is made that the nephrotic syndrome was dose-related. The aipha-mercaptopropionylglycine must be used in doses <50mg./kg. per day with regular monitoring of 24-hour urinary protein in cystinuric children. © 1979 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byPak C, Fuller C, Sakhaee K, Zerwekh J and Adams B (2018) Management of Cystine Nephrolithiasis with Alpha-MercaptopropionylglycineJournal of Urology, VOL. 136, NO. 5, (1003-1008), Online publication date: 1-Nov-1986.Harbar J, Cusworth D, Lawes L and Wrong O (2018) Comparison of 2-Mercaptopropionylglycine and D-Penicillamine in the Treatment of CystinuriaJournal of Urology, VOL. 136, NO. 1 Part 1, (146-149), Online publication date: 1-Jul-1986.Koide T, Kinoshita K, Takemoto M, Yachiku S and Sonoda T (2018) Conservative Treatment of Cystine Calculi: Effect of Oral Alpha-mercaptopropionylglycine on Cystine Stone Dissolution and on Prevention of Stone RecurrenceJournal of Urology, VOL. 128, NO. 3, (513-515), Online publication date: 1-Sep-1982. Volume 122Issue 3September 1979Page: 381-382 Advertisement Copyright & Permissions© 1979 by The American Urological Association Education and Research, Inc.Metrics Author Information G. Rizzoni More articles by this author L. Pavanello More articles by this author N. Dussini More articles by this author L. Chiandetti More articles by this author G. Zacchello More articles by this author Expand All Advertisement PDF downloadLoading ...