CRISPRDetect: A flexible algorithm to define CRISPR arrays
2016; BioMed Central; Volume: 17; Issue: 1 Linguagem: Inglês
10.1186/s12864-016-2627-0
ISSN1471-2164
AutoresAmbarish Biswas, Raymond H.J. Staals, Sergio E. Morales, Peter C. Fineran, Chris M. Brown,
Tópico(s)Innovation and Socioeconomic Development
ResumoCRISPR (clustered regularly interspaced short palindromic repeats) RNAs provide the specificity for noncoding RNA-guided adaptive immune defence systems in prokaryotes. CRISPR arrays consist of repeat sequences separated by specific spacer sequences. CRISPR arrays have previously been identified in a large proportion of prokaryotic genomes. However, currently available detection algorithms do not utilise recently discovered features regarding CRISPR loci.
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