The Induction of Adenocarcinomatous Differentiation in Neoplastic Bladder Epithelium by an Embryonic Prostatic Inductor
1982; Lippincott Williams & Wilkins; Volume: 128; Issue: 4 Linguagem: Inglês
10.1016/s0022-5347(17)53221-8
ISSN1527-3792
AutoresHirohiko Fujii, Gerald R. Cunha, Jill T. Norman,
Tópico(s)Urological Disorders and Treatments
ResumoNo AccessJournal of Urology1 Oct 1982The Induction of Adenocarcinomatous Differentiation in Neoplastic Bladder Epithelium by an Embryonic Prostatic Inductor Hirohiko Fujii, Gerald R. Cunha, and Jill T. Norman Hirohiko FujiiHirohiko Fujii More articles by this author , Gerald R. CunhaGerald R. Cunha More articles by this author , and Jill T. NormanJill T. Norman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)53221-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Epithelial cells of non-glandular, transitional cell carcinomas from rat urinary bladders were associated with embryonic rat urogenital sinus mesenchyme (a prostatic inductor) and transplanted into syngeneic adult male hosts. Neoplastic bladder epithelium formed glandular (adenocarcino-matous) acini in a substantial number of recombinants, suggesting that the mesenchyme (stroma) may influence the histotypic organization of carcinoma cells and induce the neoplastic epithelium to express a novel phenotype. © 1982 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByGITLIN J, WU X, SUN T, RITCHEY M and SHAPIRO E (2018) NEW CONCEPTS OF HISTOLOGICAL CHANGES IN EXPERIMENTAL AUGMENTATION CYSTOPLASTY: INSIGHTS INTO THE DEVELOPMENT OF NEOPLASTIC TRANSFORMATION AT THE ENTEROVESICAL AND GASTROVESICAL ANASTOMOSISJournal of Urology, VOL. 162, NO. 3 Part 2, (1096-1100), Online publication date: 1-Sep-1999.Uchida K, Samma S, Momose H, Kashihara N, Rademaker A and Oyasu R (2018) Stimulation of Urinary Bladder Tumorigenesis by Carcinogen-Exposed StromaJournal of Urology, VOL. 143, NO. 3, (618-621), Online publication date: 1-Mar-1990. Volume 128Issue 4October 1982Page: 858-861 Advertisement Copyright & Permissions© 1982 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Hirohiko Fujii More articles by this author Gerald R. Cunha More articles by this author Jill T. Norman More articles by this author Expand All Advertisement PDF DownloadLoading ...
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