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Studies on antibiotics from the genus bacillus. III. Isolation of galantins I and II, water-soluble basic peptides.

1975; Springer Nature; Volume: 28; Issue: 2 Linguagem: Inglês

10.7164/antibiotics.28.122

1881-1469

JUN''ICHI SHOJI, RYUZI SAKAZAKI, Yoshiharu Wakisaka, Kenzo Koizumi, MIKAO MAYAMA, SHINZO MATSUURA,

Natural product bioactivities and synthesis

Two water-soluble basic antibiotics named galantins I and II were isolated from a strain resembling Bacillus pulvifaciens. Both antibiotics are peptides containing glycine, alanine, ornithine, lysine and some unknown ninhydrin-positive components. An approximate empirical formula C50 plus and minus H98plus and minus 2O17N16 is indicated for galantin I. These are active against some gram-positive, acid-fast and gram-negative bacteria.