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STUDIES ON THE EPIDEMIOLOGY, MICROBIOLOGY AND IMMUNOLOGY OF TRACHOMA AMONG CHILDREN AT THREE CENTRES IN WESTERN AUSTRALIA

1973; Wiley; Volume: 2; Issue: 8 Linguagem: Inglês

10.5694/j.1326-5377.1973.tb115111.x

1326-5377

Doris M. Graham, Roger Nichols, Ida Mann,

Pediatric health and respiratory diseases

At Moora, Carnarvon and Onslow, Western Australia, 193 Aboriginal and 40 Caucasian children were examined for trachoma. Seventy-six per cent of the Aboriginals and five per cent of the Caucasians had the disease in an active form. Specimens from 38 Aboriginal children were examined. Typical trachoma inclusions were detected by immunofluorescence in 23% and isolations of chlamydia were made In chick embryo yolk sacs from 33% of conjunctival scrapings. Eleven of the isolates obtained serotyped as Type 2 and for the first time outside Africa and the Middle East, one strain was found to be Type 1. All isolates possessed biological and serological properties that classified them as trachoma agents. Antibodies against trachoma were detected by immunofluorescence in 44% of eye secretions and 78% of plasma samples.