Portal de Periódicos da CAPES

The Role of Selective Lymphadenectomy in Breast Cancer

1997; SAGE Publishing; Volume: 4; Issue: 3 Linguagem: Inglês

10.1177/107327489700400302

1526-2359

Douglas S. Reintgen, Emmanuella Joseph, Gary H. Lyman, T. Yeatman, Lodovico Balducci, Ni Ni Ku, Claudia G. Berman, Alan R. Shons, Karen Wells, John Horton, Harvey Greenberg, Santo V. Nicosia, Robert A. Clark, Steven C. Shivers, Weiguo Li, Xiangning Wang, Alan Cantor, Charles Cox,

Breast Lesions and Carcinomas

BACKGROUND: Axillary node dissection is considered a standard staging procedure in patients with breast cancer. The procedure is associated with significant morbidity and provides pathologists with many lymph nodes to evaluate. METHODS: A total of 174 women participated in a trial that included preoperative lymphoscintigraphy and intraoperative lymphatic mapping using a combination of a vital blue dye and radiocolloid mapping. RESULTS: The intraoperative lymphatic mapping correctly identified a sentinel lymph node (SLN) in 160 (92%) of 174 patients. One skip metastasis (0.7%) occurred in 136 women who had a subsequent complete node dissection. CONCLUSIONS: Lymphatic mapping and SLN biopsy using a combination of mapping techniques provide accurate nodal staging for women with breast cancer. With this technique, approximately 70% to 80% of women with no axillary metastases could be spared the morbidity of a complete node dissection.