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Long-Term Urinary Continence and Renal Function in Neonates with Posterior Urethral Valves

1990; Lippincott Williams & Wilkins; Volume: 144; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(17)39695-7

1527-3792

John P. Connor, Kevin A. Burbige,

Urinary Bladder and Prostate Research

No AccessJournal of UrologyPediatric Articles1 Nov 1990Long-Term Urinary Continence and Renal Function in Neonates with Posterior Urethral Valves John P. Connor, and Kevin A. Burbige John P. ConnorJohn P. Connor , and Kevin A. BurbigeKevin A. Burbige View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)39695-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Posterior urethral valves are known to be associated with considerable morbidity and mortality especially in the neonate. Recently the role of bladder dysfunction in the pathophysiology of renal function impairment and urinary incontinence after valve ablation has been questioned. From 1976 to 1986 we treated 50 male newborns with posterior urethral valves at our institution. Initial treatment in all cases consisted of bladder drainage by a urethral catheter, and correction of existing fluid and electrolyte abnormalities. Subsequent treatment was dictated by the degree of upper tract abnormalities and it included valve ablation alone in 24 patients, vesicostomy and later valve ablation in 8, valve ablation and later upper tract reconstruction in 14 and cutaneous ureterostomy in 4. Followup ranges from 2 to 12 years (mean 6.8). Long-term renal functional impairment was related to the serum creatinine at age 1 year. If the serum creatinine was below 1.0mg.% all patients (31) had normal values at long-term followup and if it was greater than 1.0mg.% (19) then only 7 patients had normal values at followup. Urinary continence was assessed in 42 patients and it was normal in 34 (81%). The etiology of incontinence in the remaining 8 patients was bladder dysfunction in 6 and sphincter incompetence in 2. Those patients with urinary incontinence also had a high incidence of upper tract abnormalities (6 of 8, 75%) compared to continent valve patients (10 of 34, 29%). (J. Urol., 144: 1209–1211, 1990) © 1990 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByCapitanucci M, Marciano A, Zaccara A, La Sala E, Mosiello G and De Gennaro M (2018) Long-Term Bladder Function Followup in Boys with Posterior Urethral Valves: Comparison of Noninvasive vs Invasive Urodynamic StudiesJournal of Urology, VOL. 188, NO. 3, (953-957), Online publication date: 1-Sep-2012.Sarhan O, El-Ghoneimi A, Helmy T, Dawaba M, Ghali A and Ibrahiem E (2011) Posterior Urethral Valves: Multivariate Analysis of Factors Affecting the Final Renal OutcomeJournal of Urology, VOL. 185, NO. 6S, (2491-2496), Online publication date: 1-Jun-2011.Ansari M, Surdas R, Barai S, Srivastava A and Kapoor R (2018) Renal Function Reserve in Children With Posterior Urethral Valve: A Novel Test to Predict Long-Term OutcomeJournal of Urology, VOL. 185, NO. 6, (2329-2333), Online publication date: 1-Jun-2011.Tikkinen K, Heikkilä J, Rintala R, Tammela T and Taskinen S (2018) Lower Urinary Tract Symptoms in Adults Treated for Posterior Urethral Valves in Childhood: Matched Cohort StudyJournal of Urology, VOL. 186, NO. 2, (660-666), Online publication date: 1-Aug-2011.Heikkilä J, Rintala R and Taskinen S (2018) Vesicoureteral Reflux in Conjunction With Posterior Urethral ValvesJournal of Urology, VOL. 182, NO. 4, (1555-1560), Online publication date: 1-Oct-2009.Sarhan O, Zaccaria I, Macher M, Muller F, Vuillard E, Delezoide A, Sebag G, Oury J, Aigrain Y and El-Ghoneimi A (2018) Long-Term Outcome of Prenatally Detected Posterior Urethral Valves: Single Center Study of 65 Cases Managed by Primary Valve AblationJournal of Urology, VOL. 179, NO. 1, (307-313), Online publication date: 1-Jan-2008.GHANEM M, WOLFFENBUTTEL K, DE VYLDER A and NIJMAN R (2018) LONG-TERM BLADDER DYSFUNCTION AND RENAL FUNCTION IN BOYS WITH POSTERIOR URETHRAL VALVES BASED ON URODYNAMIC FINDINGSJournal of Urology, VOL. 171, NO. 6 Part 1, (2409-2412), Online publication date: 1-Jun-2004.GLASSBERG K (2018) THE VALVE BLADDER SYNDROME: 20 YEARS LATERJournal of Urology, VOL. 166, NO. 4, (1406-1414), Online publication date: 1-Oct-2001.JAUREGUIZAR E, LOPEZ PEREIRA P, MARTINEZ URRUTIA M, ESPINOSA L and LOBATO R (2018) DOES NEONATAL PYELOURETEROSTOMY WORSEN BLADDER FUNCTION IN CHILDREN WITH POSTERIOR URETHRAL VALVES?Journal of Urology, VOL. 164, NO. 3 Part 2, (1031-1034), Online publication date: 1-Sep-2000.EL-GHONEIMI A, DESGRIPPES A, LUTON D, MACHER M, GUIBOURDENCHE J, GAREL C, MULLER F, VUILLARD E, LOTTMANN H, NESSMANN C, OURY J and AIGRAIN Y (2018) OUTCOME OF POSTERIOR URETHRAL VALVES: TO WHAT EXTENT IS IT IMPROVED BY PRENATAL DIAGNOSIS?Journal of Urology, VOL. 162, NO. 3 Part 1, (849-853), Online publication date: 1-Sep-1999.Freedman A, Bukowski T, Smith C, Evans M, Johnson M and Gonzalez R (2018) Fetal Therapy for Obstructive Uropathy: Specific Outcomes DiagnosisJournal of Urology, VOL. 156, NO. 2S, (720-724), Online publication date: 1-Aug-1996.Smith G, Canning D, Schulman S, Snyder H and Duckett J (2018) The Long-Term Outcome of Posterior Urethral Valves Treated with Primary Valve Ablation and ObservationJournal of Urology, VOL. 155, NO. 5, (1730-1734), Online publication date: 1-May-1996.Holmdahl G, Sillen U, Hanson E, Hermansson G and Hjalmas K (2018) Bladder Dysfunction in Boys with Posterior Urethral Valves before and after PubertyJournal of Urology, VOL. 155, NO. 2, (694-698), Online publication date: 1-Feb-1996.Holmdahl G, Sillen U, Bachelard M, Hansson E, Hermansson G, Hjalmas K and Bauer S (2018) The Changing Urodynamic Pattern in Valve Bladders During InfancyJournal of Urology, VOL. 153, NO. 2, (463-467), Online publication date: 1-Feb-1995.Hutton K, Thomas D, Arthur R, Irving H and Smith S (2018) Prenatally Detected Posterior Urethral Valves: Is Gestational age at Detection a Predictor of Outcome?Journal of Urology, VOL. 152, NO. 2 Part 2, (698-701), Online publication date: 1-Aug-1994.Ross J, Kay R, Novick A, Hayes J, Hodge E and Streem S (2018) Long-Term Results of Renal Transplantation into the Valve BladderJournal of Urology, VOL. 151, NO. 6, (1500-1504), Online publication date: 1-Jun-1994.Reinberg Y, de Castano I and Gonzalez R (2018) Influence of Initial Therapy on Progression of Renal Failure and Body Growth in Children with Posterior Urethral ValvesJournal of Urology, VOL. 148, NO. 2 Part 2, (532-533), Online publication date: 1-Aug-1992.Merguerian P, McLorie G, Churchill B, McKenna P and Khoury A (2018) Radiographic and Serologic Correlates of Azotemia in Patients with Posterior Urethral ValvesJournal of Urology, VOL. 148, NO. 5 Part 1, (1499-1503), Online publication date: 1-Nov-1992. Volume 144Issue 5November 1990Page: 1209-1211 Advertisement Copyright & Permissions© 1990 by The American Urological Association Education and Research, Inc.MetricsAuthor Information John P. Connor More articles by this author Kevin A. Burbige More articles by this author Expand All Advertisement Loading ...