Clindamycin versus metronidazole in the treatment of bacterial vaginosis.
1988; National Institutes of Health; Volume: 72; Issue: 5 Linguagem: Inglês
Autores
Wayne Greaves, J Chungafung, Barbara A. Morris, Ashagrachew Haile, Jennifer Townsend,
Tópico(s)COVID-19 Impact on Reproduction
ResumoOne hundred forty-three women with complaints of vaginitis were assigned to receive either 500 mg of metronidazole twice daily for 7 days or clindamycin 300 mg twice daily for 7 days. There was no significant difference in the failure rate between patients treated with clindamycin (6.1%) and those treated with metronidazole (4%). Adverse reactions were infrequent and mild in both treatment groups. Three patients who received clindamycin developed non-bloody diarrhea, which was mild and did not necessitate discontinuing therapy. We conclude that clindamycin may be a safe and effective alternative to metronidazole for treating women with bacterial vaginosis.
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