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Fatal Disseminated Acanthamoeba lenticulata Acanthamebiasis in a Heart Transplant Patient

2007; Centers for Disease Control and Prevention; Volume: 13; Issue: 5 Linguagem: Inglês

10.3201/eid1305.061347

1080-6059

Stéphane Barète, Alain Combes, Johan F. De Jonckheere, A. Datry, Shaïda Varnous, Valérie Martinez, Sara García Ptacek, Éric Caumes, Frédérique Capron, Camille Françès, Claude Gibert, O. Chosidow,

Heme Oxygenase-1 and Carbon Monoxide

Abstract We report a fatal case of disseminated acanthamebiasis caused by Acanthamoeba lenticulata (genotype T5) in a 39-year-old heart transplant recipient. The diagnosis was based on skin histopathologic results and confirmed by isolation of the ameba from involved skin and molecular analysis of a partial 18S rRNA gene sequence (DF3).