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Idiopathic Autoimmune Thrombocytopenic Purpura

1994; Elsevier BV; Volume: 41; Issue: 1 Linguagem: Inglês

10.1016/s0065-3101(24)00092-6

1878-1926

Joanne Kurtzberg, J.A. Stockman,

Immunodeficiency and Autoimmune Disorders

Childhood ITP occurs in acute and chronic forms. In general, both diseases are mild and can be managed conservatively. Approaches to therapy are highly controversial and vary widely among pediatricians and academic centers. Approximately 5% of children with ITP will develop chronic disease with severe thrombocytopenia and bleeding. These children require therapy, which is often expensive and not without risk of development of late adverse effects.