Portal de Periódicos da CAPES

Wearable System for Acquisition, Processing and Storage of the Signal from Amperometric Glucose Sensors

1991; SAGE Publishing; Volume: 14; Issue: 3 Linguagem: Inglês

10.1177/039139889101400310

1724-6040

P.G. Fabietti, M. Massi Benedetti, Frank Bronzo, Gianpaolo Reboldi, E. Sarti, P. Brunetti,

Biosensors and Analytical Detection

A wearable device for the acquisition, processing and storage of the signal from needle-type glucose sensors has been designed and developed as part of a project aimed at developing a portable artificial pancreas. The device is essential to assess the operational characteristics of miniaturized sensors in vivo. It can be connected to sensors operating at a constant potential of 0.65 Volts, and generating currents in the order of 10 –9 Amp. It is screened and equipped with filters that permit data recording and processing even in the presence of electrical noise. It can operate with sensors with different characteristics (1–200 nA full scale). The device has been designed to be worn by patients, so its weight and size have been kept to a minimum (250 g; 8.5 × 14.5 × 3.5 cm). It is powered by rechargeable Ni/Cd batteries allowing continuous operation for 72 h. The electronics consists of an analog card with operational amplifiers, and a digital one with a microprocessor (Intel 80C196, MCS-96 class, with internal 16-bit CPU supporting programs written in either C or Assembler language), a 32 Kb EPROM, and an 8 Kb RAM where the data are stored. The microprocessor can run either at 5 or 10 Mhz and features on-chip peripherals: an analog/digital (AID) converter, a serial port (used to transfer data to a Personal Computer at the end of the 72 h), input-output (I/O) units at high-speed, and two timers. The device is programmed and prepared to operate by means of a second hand-held unit equipped with an LCD display and a 16-key numeric pad. The hand-held unit is easily connected to the wearable one to calibrate the sensor, display alarms and system fault messages.