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Validation of the laboratory risk indicator for necrotising fasciitis scoring system (LRINEC) in a Northern European population

2016; Elsevier BV; Volume: 70; Issue: 1 Linguagem: Inglês

10.1016/j.bjps.2016.05.014

1878-0539

Ahmed Al‐Hindawi, James McGhee, Joseph Lockey, Marcela P. Vizcaychipi,

Antimicrobial Resistance in Staphylococcus

Necrotising fasciitis is a disease with an estimated incidence of 0.24–0.4 per 100,000. It is known by clinicians and the public as "flesh eating bacteria" and is associated with high morbidity and a mortality of up to 76%.1 The presentation of necrotising fasciitis can be insidious and non-specific. Gangrene ultimately develops with associated pyrexia and septic shock over 24–72 h.2 Early recognition and aggressive treatment with antimicrobials and surgical debridement improves outcomes.