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Adenocarcinoma of the Urachus Associated with Elevated Levels of CA 125

1991; Lippincott Williams & Wilkins; Volume: 145; Issue: 1 Linguagem: Inglês

10.1016/s0022-5347(17)38271-x

1527-3792

Steven E. Guarnaccia, Vernon M. Pais, John Grous, Nicholas Spirito,

Gastrointestinal disorders and treatments

No AccessJournal of Urology1 Jan 1991Adenocarcinoma of the Urachus Associated with Elevated Levels of CA 125 Steven Guarnaccia, Vernon Pais, John Grous, and Nicholas Spirito Steven GuarnacciaSteven Guarnaccia More articles by this author , Vernon PaisVernon Pais More articles by this author , John GrousJohn Grous More articles by this author , and Nicholas SpiritoNicholas Spirito More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)38271-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Adenocarcinoma of the urachus is a rare genitourinary tumor with a poor prognosis. The treatment of choice is en bloc surgical resection, although combination therapy with surgery and chemotherapy has been used with mixed results. We describe a 69-year-old woman with adenocarcinoma of the urachus and elevated serum levels of CA 125 tumor marker. She was treated with resection plus 5-fluorouracil, doxorubicin and mitomycin, alternating with platinum-based chemotherapy. The serum CA 125 level decreased precipitously after the operation and became normal after 2 months of chemotherapy. The patient remained free of disease 1 year postoperatively. Serum CA 125 may be a useful tumor marker for urachal carcinoma and adjuvant chemotherapy may be effective in treating the disease. © 1991 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byIZES J, DYER M, CALLUM M, BANKES P, LIBERTINO J and CAFFREY J (2018) CA 125 AS A MARKER OF TUMOR ACTIVITY IN ADVANCED UROTHELIAL MALIGNANCYJournal of Urology, VOL. 165, NO. 6 Part 1, (1908-1913), Online publication date: 1-Jun-2001. Volume 145 Issue 1 January 1991 Page: 140-141 Advertisement Copyright & Permissions© 1991 by The American Urological Association Education and Research, Inc.KeywordscarcinomaUrachusAdenocarcinomaantigens, tumor-associated, carbohydratebladder neoplasmsMetrics Author Information Steven Guarnaccia More articles by this author Vernon Pais More articles by this author John Grous More articles by this author Nicholas Spirito More articles by this author Expand All Advertisement PDF downloadLoading ...