Cyclosporine-A as prevention for graft-versus-host disease in pediatric patients undergoing bone marrow transplants.
1990; National Institutes of Health; Volume: 17; Issue: 1 Linguagem: Inglês
Autores Tópico(s)
Hematological disorders and diagnostics
ResumoCyclosporine-A is a drug commonly used in bone marrow transplantation (BMT) for the prevention of graft-versus-host disease. In the pediatric allogeneic BMT population at The Children's Hospital in Boston, a combination of Cyclosporine-A and Methotrexate is used for graft-versus-host prophylaxis. Graft-versus-host disease, whether acute or chronic, may be fatal. The increasing use of Cyclosporine-A in the pediatric BMT setting demands careful nursing assessment and intervention for Cyclosporine-A toxicity and related side effects.
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