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Prophylactic Antibiotics in Transurethral Prostatectomy

1981; Lippincott Williams & Wilkins; Volume: 126; Issue: 1 Linguagem: Inglês

10.1016/s0022-5347(17)54380-3

1527-3792

Ole Steen Nielsen, Svend Maigaard, Niels Frimodt‐Møller, Paul O. Madsen,

Surgical site infection prevention

No AccessJournal of Urology1 Jul 1981Prophylactic Antibiotics in Transurethral Prostatectomy Ole S. Nielsen, Svend Maigaard, Niels Frimodt-Møller, and Paul O. Madsen Ole S. NielsenOle S. Nielsen , Svend MaigaardSvend Maigaard , Niels Frimodt-MøllerNiels Frimodt-Møller , and Paul O. MadsenPaul O. Madsen View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)54380-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail There were 110 patients with preoperative sterile urine who underwent transurethral resection of the prostate and were included in a prospective, randomized, double-blind study that compared the effects of cefoxitin, a cephalosporin, to a placebo. The 2 treatment groups were comparable in age, weight of patient, general condition, diagnosis, preoperative instrumentation, operating time, weight of resected tissue and blood loss. Cefoxitin significantly lowered the incidence of infection, as indicated 3 and 7 days postoperatively, from 26.4 to 3.9 per cent and from 42 to 6.5 per cent, respectively. We were not able to correlate infection to age, general condition, diagnosis, operating time, preoperative instrumentation, weight of resected tissue or blood loss. No statistical difference was found between the 2 treatment groups in the incidence and degree of postoperative fever. These data suggest that prophylactic antibiotics should be administered preoperatively to uninfected patients who undergo transurethral resection of the prostate to prevent postoperative urinary tract infection. © 1981 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByQIANG W, JIANCHEN W, MacDONALD R, MONGA M and WILT T (2018) ANTIBIOTIC PROPHYLAXIS FOR TRANSURETHRAL PROSTATIC RESECTION IN MEN WITH PREOPERATIVE URINE CONTAINING LESS THAN 100,000 BACTERIA PER ML: A SYSTEMATIC REVIEWJournal of Urology, VOL. 173, NO. 4, (1175-1181), Online publication date: 1-Apr-2005.BERRY A and BARRATT A (2018) PROPHYLATIC ANTIBIOTIC USE IN TRANSURETHRAL PROSTATIC RESECTION: A META-ANALYSISJournal of Urology, VOL. 167, NO. 2 Part 1, (571-577), Online publication date: 1-Feb-2002.Mebust W, Holtgrewe H, Cockett A, Peters P and Writing Committee (2018) Transurethral prostatectomy: Immediate and postoperative complications. A cooperative study of 13 participating institutions evaluating 3,885 patientsJournal of Urology, VOL. 167, NO. 2 Part 2, (999-1003), Online publication date: 1-Feb-2002.MEBUST W, HOLTGREWE H, COCKETT A and PETERS P (2018) TRANSURETHRAL PROSTATECTOMY: IMMEDIATE AND POSTOPERATIVE COMPLICATIONS. COOPERATIVE STUDY OF 13 PARTICIPATING INSTITUTIONS EVALUATING 3,885 PATIENTSJournal of Urology, VOL. 167, NO. 1, (5-9), Online publication date: 1-Jan-2002.Viitanen J, Talja M, Jussila E, Nurmi M, Permi J, Puolakka V, Rintala E, Salmela H, Tiitinen J, Tuhkanen K and Elo J (2018) Randomized Controlled Study of Chemoprophylaxis in Transurethral ProstatectomyJournal of Urology, VOL. 150, NO. 5 Part 2, (1715-1717), Online publication date: 1-Nov-1993.Crawford E, Berger N, Davis M and Donohue R (2018) Prevention of Urinary Tract Infection and Bacteremia Following Transurethral Surgery: Oral Lomefloxacin Compared to Parenteral CefotaximeJournal of Urology, VOL. 147, NO. 4, (1053-1055), Online publication date: 1-Apr-1992.Slavis S, Miller J, Golji H and Dunshee C (2018) Comparison of Single-Dose Antibiotic Prophylaxis in Uncomplicated Transurethral Resection of the ProstateJournal of Urology, VOL. 147, NO. 5, (1303-1306), Online publication date: 1-May-1992.Roberts J (2018) Editorial CommentsJournal of Urology, VOL. 147, NO. 4, (1055-1055), Online publication date: 1-Apr-1992.Schaeffer A (2018) Editorial CommentsJournal of Urology, VOL. 147, NO. 4, (1055-1055), Online publication date: 1-Apr-1992. (2018) Reply By AuthorsJournal of Urology, VOL. 147, NO. 4, (1055-1055), Online publication date: 1-Apr-1992.Houle A, Mokhless I, Sarto N and Elhilali M (2018) Perioperative Antibiotic Prophylaxis for Transurethral Resection of the Prostate: Is it Justifiable?Journal of Urology, VOL. 142, NO. 2 Part 1, (317-319), Online publication date: 1-Aug-1989.Mebust W, Holtgrewe H, Cockett A and Peters P (2018) Transurethral Prostatectomy: Immediate and Postoperative Complications. A Cooperative Study of 13 Participating Institutions Evaluating 3,885 PatientsJournal of Urology, VOL. 141, NO. 2, (243-247), Online publication date: 1-Feb-1989.Gorelick J, Senterfit L and Vaughan E (2018) Quantitative Bacterial Tissue Cultures From 209 Prostatectomy Specimens: Findings and ImplicationsJournal of Urology, VOL. 139, NO. 1, (57-60), Online publication date: 1-Jan-1988.Desai K, Abrams P and White L (2018) A Double-blind Comparative Trial of Short-term Orally Administered Enoxacin in the Prevention of Urinary Infection after Elective Transurethral Prostatectomy: A Clinical and Pharmacokinetic StudyJournal of Urology, VOL. 139, NO. 6, (1232-1234), Online publication date: 1-Jun-1988.Grabe M (2018) Antimicrobial Agents in Transurethral Prostatic ResectionJournal of Urology, VOL. 138, NO. 2, (245-252), Online publication date: 1-Aug-1987.Prokocimer P, Quazza M, Gibert C, Lemoine J, Joly M, Dureuil B, Moulonguet A, Manuel C and Desmonts J (2018) Short-Term Prophylactic Antibiotics in Patients Undergoing Prostatectomy: Report of a Double-Blind Randomized Trial with 2 Intravenous Doses of CefotaximeJournal of Urology, VOL. 135, NO. 1, (60-64), Online publication date: 1-Jan-1986.Childs S, Wells W and Mirelman S (2018) Antibiotic Prophylaxis for Genitourinary Surgery in Community HospitalsJournal of Urology, VOL. 130, NO. 2, (305-308), Online publication date: 1-Aug-1983.Kunin C (2018) Editorial CommentJournal of Urology, VOL. 130, NO. 2, (308-308), Online publication date: 1-Aug-1983. Volume 126Issue 1July 1981Page: 60-62 Advertisement Copyright & Permissions© 1981 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Ole S. Nielsen More articles by this author Svend Maigaard More articles by this author Niels Frimodt-Møller More articles by this author Paul O. Madsen More articles by this author Expand All Advertisement PDF DownloadLoading ...