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Renal Function in Unilateral Nephrectomy Subjects

1992; Lippincott Williams & Wilkins; Volume: 147; Issue: 2 Linguagem: Inglês

10.1016/s0022-5347(17)37230-0

1527-3792

Pei-Ling Liu, Eileen D.M. Gallery, Roslyn Grigg, J. F. Mahony, Á. Z. Györy,

Chronic Kidney Disease and Diabetes

No AccessJournal of Urology1 Feb 1992Renal Function in Unilateral Nephrectomy Subjects Pei-Ling Liu, Eileen D. Gallery, Roslyn Grigg, John F. Mahony, and Akos Z. Gyory Pei-Ling LiuPei-Ling Liu More articles by this author , Eileen D. GalleryEileen D. Gallery More articles by this author , Roslyn GriggRoslyn Grigg More articles by this author , John F. MahonyJohn F. Mahony More articles by this author , and Akos Z. GyoryAkos Z. Gyory More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)37230-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Renal function in 32 subjects who had undergone unilateral nephrectomy (17 transplant donors and 15 subjects with unilateral renal disease) was compared with that of 22 normal subjects. The age-adjusted glomerular filtration rate was lower in transplant donors (79 ± 15% of normal) than in those whose nephrectomy was performed for unilateral renal disease (90 ± 12% of normal). The donors were also significantly older at nephrectomy (48 ± 10 years versus 24 ± 13 years, p <0.001). This finding may represent less capacity for compensatory hypertrophy. Proximal tubular and medullary function as assessed by 15-minute phenolsulfonphthalein excretion, maximum urinary concentration in response to water deprivation plus exogenous vasopressin, and urinary acidification in response to an oral acid load were all within normal limits for glomerular filtration rate. Overall renal function was well preserved after nephrectomy. A small number of patients did have increased cast excretion, which may signify the presence of mild renal disease in these subjects. © 1992 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByLent V and Harth J (2018) Nephropathy in Remnant Kidneys: Pathological Proteinuria After Unilateral NephrectomyJournal of Urology, VOL. 152, NO. 2 Part 1, (312-316), Online publication date: 1-Aug-1994. Volume 147Issue 2February 1992Page: 337-339 Advertisement Copyright & Permissions© 1992 by The American Urological Association Education and Research, Inc.Keywordsnephrectomykidney diseasesrenal function testskidney transplantationMetricsAuthor Information Pei-Ling Liu More articles by this author Eileen D. Gallery More articles by this author Roslyn Grigg More articles by this author John F. Mahony More articles by this author Akos Z. Gyory More articles by this author Expand All Advertisement PDF DownloadLoading ...