Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal Gammopathy and Skin Changes (Poems) Syndrome
1994; Cambridge University Press; Volume: 21; Issue: 1 Linguagem: Inglês
10.1017/s0317167100048794
ISSN2057-0155
Autores Tópico(s)Autoimmune Bullous Skin Diseases
ResumoA patient with a three year history of POEMS syndrome-polyneuropathy, hepatosplenomegaly M-protein, skin changes, optic disc edema, peripheral oedema, pleuritis, lymphadenopathy, and osteosclerotic myeloma is described. The patient had a twenty year history of psoriasis and impotence was the first sign of the disease. The pathophysiology of this multisystem disorder is unknown, although the M-protein is essential. No improvement was found after radiation, chemotherapy and steroid treatment.
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