Artigo Revisado por pares

THYROTOXICOSIS IN DOWN'S AND TURNER'S SYNDROMES: THE LIKELIHOOD OF HASHIMOTO'S THYROIDITIS AS THE UNDERLYING AETIOLOGY

2000; Wiley; Volume: 54; Issue: 4 Linguagem: Inglês

10.1111/j.1742-1241.2000.tb11902.x

ISSN

1742-1241

Autores

Iskandar Idris, BP O'Malley,

Tópico(s)

Blood groups and transfusion

Resumo

SUMMARY Biochemical thyrotoxicosis in young women is almost invariably due to Graves' disease. Its occurrence in females with Turner's and Down's syndromes, both of which are seldom associated with Graves' hyperthyroidism but are frequently allied to Hashimoto's thyroiditis, should alert physicians to the possibility of the latter. The discharge thyroiditis of Hashimoto's disease can be recurrent and protracted. A brisk response to antithyroid therapy would favour a thyroiditis and, in this circumstance, radio‐iodine uptake should be reduced. The absence of TSH receptor antibodies in such cases, while not wholly refuting the notion of active Graves' disease, lends support to the existence of Hashimoto's thyroiditis. ( Int J Clin Pract 2000; 54(4) : 272‐273)

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