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Factor X deficiency in a cat

1997; American Veterinary Medical Association; Volume: 211; Issue: 5 Linguagem: Inglês

10.2460/javma.1997.211.05.576

1943-569X

Jody L. Gookin, Marjory B. Brooks, James L. Catalfamo, Susan E. Bunch, Karen R. Muñana,

Platelet Disorders and Treatments

Severe congenital deficiency of factor X was diagnosed in a 3-year-old castrated male domestic shorthair cat with clinical signs of generalized seizures and prolonged bleeding after venipuncture. Heritability of factor X deficiency was suspected because of a prolonged Russell's viper venom time in the dam and reductions in factor X activity in the dam and 1 sibling. To our knowledge, factor X deficiency in cats has not been reported previously. Definitive diagnosis for animals with clinical signs of coagulopathy may require repetition of coagulation screening tests using different assay methods or specific coagulation factor analyses.