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Factors Predicting the Outcome of Varicocele Repair for Subfertility: The Value of the Luteinizing Hormone-Releasing Hormone Test

1989; Lippincott Williams & Wilkins; Volume: 142; Issue: 5 Linguagem: Inglês

10.1016/s0022-5347(17)39040-7

1527-3792

Amitai Bickel, Gabriel Dickstein,

Plant Reproductive Biology

No AccessJournal of Urology1 Nov 1989Factors Predicting the Outcome of Varicocele Repair for Subfertility: The Value of the Luteinizing Hormone-Releasing Hormone Testis companion ofEditorial Comment Amitai Bickel, and Gabriel Dickstein Amitai BickelAmitai Bickel More articles by this author , and Gabriel DicksteinGabriel Dickstein More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)39040-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail The mechanism by which varicocele caused infertility is not yet clear. Endocrine factors have been suggested to explain impaired spermatogenesis in patients with varicocele. We conducted a prospective study on testosterone and gonadotropin levels and their response to the luteinizing hormone-releasing hormone test to determine the possible role of a hormonal defect in subfertility. Luteinizing hormone-releasing hormone tests were performed on 11 subfertile men with varicocele preoperatively and 3 months postoperatively. The differences in the luteinizing hormone response were statistically significant. The maximal luteinizing hormone levels also were significantly lower in patients whose spermiogram changed postoperatively. No significant changes were noted in testosterone and other gonadotropin levels postoperatively. A prognostic correlation between the change in response of luteinizing hormone to luteinizing hormone-releasing hormone (preoperatively and postoperatively) and improvement in fertility (pregnancy success) was found. We suggest that the luteinizing hormone-releasing hormone test should be considered to estimate the hormonal derangement and also the prognosis of an operation in subfertile men with varicocele. (J. Urol., 142: 1230-1234, 1989) © 1989 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByPodesta M, Gottlieb S, Medel R, Ropelato G, Bergada C and Quesada E (2018) Hormonal Parameters and Testicular Volume in Children and Adolescents with Unilateral Varicocele: Preoperative and Postoperative FindingsJournal of Urology, VOL. 152, NO. 2 Part 2, (794-797), Online publication date: 1-Aug-1994.Related articlesJournal of UrologyNov 13, 2018, 1:51:06 AMEditorial Comment Volume 142Issue 5November 1989Page: 1230-1234 Advertisement Copyright & Permissions© 1989 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Amitai Bickel More articles by this author Gabriel Dickstein More articles by this author Expand All Advertisement PDF DownloadLoading ...