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Analysis of Regional Norepinephrine Content in the Rabbit Bladder after Acute Electrical Pelvic Floor Stimulation

1993; Lippincott Williams & Wilkins; Volume: 150; Issue: 1 Linguagem: Inglês

10.1016/s0022-5347(17)35453-8

1527-3792

Manabu Ishigooka, Teruhiro Nakada,

Pain Mechanisms and Treatments

No AccessJournal of Urology1 Jul 1993Analysis of Regional Norepinephrine Content in the Rabbit Bladder after Acute Electrical Pelvic Floor Stimulation Manabu Ishigooka, and Teruhiro Nakada Manabu IshigookaManabu Ishigooka More articles by this author , and Teruhiro NakadaTeruhiro Nakada More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)35453-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Experiments were carried out to evaluate the regional norepinephrine (NE) content of the rabbit bladder after acute electrical pelvic floor stimulation (EPFS). After 30 minutes of EPFS, the content of NE increased significantly in both the bladder base and body (p < 0.05). Furthermore, this increased NE content continued for 1 to 2hours after cessation of stimulation. The content of NE in the bladder base and body in rabbits treated with alpha-methyl-paratyrosine (AMT) was lower than in the control group. Application of EPFS increased NE content in the bladder even in animals pretreated with AMT. Based on these findings, during EPFS the hypogastric nerve would be presumed to play a significant role in bladder inhibition. Increased synthesis of NE probably did not play an important role in elevation of NE content after EPFS. © 1993 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 150Issue 1July 1993Page: 235-238 Advertisement Copyright & Permissions© 1993 by The American Urological Association Education and Research, Inc.Keywordsbladderrabbitsnorepinephrineelectric stimulationMetricsAuthor Information Manabu Ishigooka More articles by this author Teruhiro Nakada More articles by this author Expand All Advertisement PDF DownloadLoading ...