Voltar
Artigo Revisado por pares
BIBTEX RIS

Canine fucosidosis: a biochemical and genetic investigation

1984; Elsevier BV; Volume: 36; Issue: 3 Linguagem: Inglês

10.1016/s0034-5288(18)31958-1

ISSN

1532-2661

Autores

P.J. Healy, B. R. H. Farrow, F. W. Nicholas, Karen K. Hedberg, R. Murray Ratcliffe,

Tópico(s)

Trypanosoma species research and implications

Resumo

Plasma and leucocytes from six springer spaniels with clinical signs of fucosidosis had low activities of alpha-L-fucosidase. Fucosidase activities in plasma and leucocytes from parents of springers with fucosidosis were approximately half those in non-springer dogs. Examination of pedigree information in relation to classifications based upon plasma and leucocyte assays provided convincing evidence that fucosidosis is inherited in an autosomal recessive manner and that it is possible to detect heterozygotes using plasma and leucocyte assays.

Referência(s)