Scientific Evaluation of Traditionally Known Insulin Plant Costus Species for the Treatment of Diabetes in Human
2016; Volume: 3; Issue: 6 Linguagem: Inglês
10.20546/ijcrbp.2016.306.011
ISSN2349-8080
AutoresM. Ferosekhan, A R. Mahesh, Sambandam Ravikumar,
Tópico(s)Diet, Metabolism, and Disease
ResumoMedicinal plants have a long history of use and their use is widespread in both developing and developed countries. From the last few decades, there is an increasing interest in formation of the drugs derived from plants which helps to control diseases. Also the herbal products are safer than synthetic products which may be harmful and unsafe to the human and environment. The present study made an attempt to find out the antidiabetic property of Costus species. Fresh elder leaves of species viz., Costus pictus and Costus speciosus were collected from Western Ghats, Tamil Nadu. The plant samples were washed thoroughly and extracted in ethanolic solvent. In in vitro α-amylase inhibitory study, the maximum inhibition of Costus pictus was of 88.75% at a concentration 400µg.ml-1. In starch iodine color assay, the maximum inhibition of color change of extract at 400µg.ml-1. Glucose uptake inhibition assay data suggests Costus species is significant in inhibiting glucose diffusion. It is concluded from the present study that the Costus species extracts potentiate the antidiabetic activity and can be used as an alternate for the treatment of diabetes after completing successful clinical trials
Referência(s)