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Gastrin-related peptides as stimulants of pancreatic and gastric secretion

1969; American Physiological Society; Volume: 217; Issue: 1 Linguagem: Inglês

10.1152/ajplegacy.1969.217.1.262

2163-5773

G. Frank Stening, Grossman Mi,

Diabetes Treatment and Management

ARTICLESGastrin-related peptides as stimulants of pancreatic and gastric secretionGF Stening, and MI GrossmanGF Stening, and MI GrossmanPublished Online:01 Jul 1969https://doi.org/10.1152/ajplegacy.1969.217.1.262MoreSectionsPDF (924 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Cited ByControl of pancreatic secretion in humansAdvances in Medical Sciences, Vol. 55, No. 1The effect of acute ethanol administration on the exocrine pancreatic secretion of the pig7 December 2005 | British Journal of Surgery, Vol. 62, No. 9Synthesis of N-terminal substituted anthranilic acid dimer derivatives for evaluation on CCK receptorsIl Farmaco, Vol. 56, No. 8Plasma Gastrin Levels in Alcoholic and Idiopathic Chronic Pancreatitis Patients Free from Helicobacter Pylori InfectionAnnals of Saudi Medicine, Vol. 21, No. 1-2Study of salivary response to continuous infusion of cerulein and secretin in healthy subjectsOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, Vol. 89, No. 1Effects of spiroglumide, a gastrin receptor antagonist, on acid secretion in humans24 December 2001 | European Journal of Clinical Investigation, Vol. 29, No. 2Cellular and Molecular Targets of GastrinA Review: Acute and Chronic Effects of Ethanol and Alcoholic Beverages on the Pancreatic Exocrine Secretion In Vivo and In VitroAlcoholism: Clinical and Experimental Research, Vol. 22, No. 7CCKB/gastrin receptor antagonists as potential drugs for peptic ulcer therapyDrug Discovery Today, Vol. 2, No. 7Cholecystokinin Decreases Food Intake in Rats 16 September 2012 | Obesity Research, Vol. 5, No. 3Cytosolic Ca2+ evaluation in rabbit parietal cells: a novel method to screen gastrin receptor antagonistsEuropean Journal of Pharmacology, Vol. 306, No. 1-3Cholecystokinin is not a physiological regulator of gastric pepsin secretion in ratsJournal of Gastroenterology, Vol. 30, No. 4Biological actions of cholecystokininPeptides, Vol. 15, No. 45 Gut hormones in gastric functionBaillière's Clinical Endocrinology and Metabolism, Vol. 8, No. 1Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonistsBioorganic & Medicinal Chemistry Letters, Vol. 3, No. 5Different effects of CCK antagonists on gastric-acid response to CCK and pentagastrinPeptides, Vol. 14, No. 2POSTER COMMUNICATIONS19 July 2012 | British Journal of Pharmacology, Vol. 107, No. S2Effect of loxiglumide on basal and gastrinand bombesin-stimulated gastric acid and serum gastrin levelsGastroenterology, Vol. 103, No. 4Characterization of antigastrin activity in vivo of CR 2194, a new R-4-benzamido-5-oxo-pentanoic acid derivativeEuropean Journal of Pharmacology, Vol. 216, No. 2Cholecystokinin receptor antagonist MK-329 blocks intestinal fat-induced inhibition of meal-stimulated gastric acid secretionGastroenterology, Vol. 102, No. 1Neural and hormonal mechanisms mediate the enterogastric reflex: A study in intestinal transplants in ratsGastroenterology, Vol. 101, No. 3Effect of cholecystokinin receptor antagonists, MK-329 and L-365,260, on cholecystokinin-induced acid secretion and histidine decarboxylase activity in the ratRegulatory Peptides, Vol. 35, No. 1Role of cholecystokinin in the control of gastric somatostatin in the rat: in vivo and in vitro studiesRegulatory Peptides, Vol. 32, No. 3Stimulatory effect of pancreastatin on gastric acid secretion in conscious dogsGastroenterology, Vol. 99, No. 1Visualisation of the gastrin receptor within rat mucosa using a biotinylated gastrin antagonist12 January 2009 | International Journal of Peptide and Protein Research, Vol. 35, No. 4Effects of an antral mucosectomy, L-364,718 and atropine on cephalic phase of gastric and pancreatic secretion in dogsGastroenterology, Vol. 98, No. 1Effects of lorglumide on gastrin- and peptone-stimulated gastric acid secretion in ratsLife Sciences, Vol. 47, No. 26Does Sulfation of Gastrin Influence Gastric Acid Secretion in Man?8 July 2009 | Scandinavian Journal of Gastroenterology, Vol. 25, No. 7Cholecystokinin1 January 2011Nutritional Support in Acute PancreatitisGastroenterology Clinics of North America, Vol. 18, No. 3Importance of sulfation of gastrin or cholecystokinin (CCK) on affinity for gastrin and CCK receptorsPeptides, Vol. 10, No. 4Common or distinct receptors for gastrin and cholecystokinin in gastric mucosa?Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol. 1010, No. 3Effect of cholecystokinin receptor antagonist on pancreatic responses to exogenous gastrin and cholecystokinin and to meal stimuliGastroenterology, Vol. 94, No. 4Association of cholecystectomy with pancreatic growth and increased plasma levels of cholecystokinin in the syrian golden hamsterJournal of Surgical Research, Vol. 44, No. 3Vagal Influence on Cholecystokinin and Neurotensin Release in Conscious Dogs8 July 2009 | Scandinavian Journal of Gastroenterology, Vol. 23, No. 3Biological effects of a proglumide derivative as cholecystokinin antagonist in conscious dogsRegulatory Peptides, Vol. 18, No. 3-4Separation of protein hormonesJournal of Chromatography B: Biomedical Sciences and Applications, Vol. 418Additive interaction of pentagastrin and secretin on pancreatic growth in ratsGastroenterology, Vol. 92, No. 2Cholecystokinetic and Pancreozymic Effect of O-Sulfated Gastrin Compared With Nonsulfated Gastrin and CholecystokininGastroenterology, Vol. 91, No. 5High plasma cholecystokinin response following ingestion of test meal by patients with non-insulin dependent diabetes mellitusRegulatory Peptides, Vol. 14, No. 3Structure-activity relationship of subtypes of cholecystokinin receptors in the cat lower esophageal sphincterGastroenterology, Vol. 90, No. 1Cimetidine and postprandial pancreatic exocrine secretion in dogsAgents and Actions, Vol. 17, No. 2Rat immunoreactive cholecystokinin (CCK): characterization using two chromatographic techniquesRegulatory Peptides, Vol. 11, No. 2Species variation in the tyrosine sulfation of mammalian gastrinsGeneral and Comparative Endocrinology, Vol. 58, No. 1Effect of CCK antibodies on food intake and weight gain in zucker ratsPhysiology & Behavior, Vol. 34, No. 2Acute and Chronic Actions of Alcohol on Pancreatic Exocrine Secretion in Humans and AnimalsRelationship of CCK/gastrin receptor binding to amylase release in dog pancreatic aciniRegulatory Peptides, Vol. 10, No. 1Regulation of Pancreatic SecretionClinics in Gastroenterology, Vol. 13, No. 3Sham feeding and pancreatic secretionGastroenterology, Vol. 87, No. 1Pharmacologic Aspects of Intestinal Permeability to Lipids (Except Steroids and Fat-Soluble Vitamins)Somatostatin, prostaglandin E2 and atropine inhibition of the gastric actions of bombesin in the dogPeptides, Vol. 5, No. 1Measurement and occurrence of sulfated gastrins8 July 2009 | Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 44, No. sup168Release of Cholecystokinin in Conscious Dogs; Correlation With Simultaneous Measurements of Gallbladder Pressure and Pancreatic Protein SecretionGastroenterology, Vol. 85, No. 5Human Protein Digestion and Absorption: Normal Mechanisms and Protein-energy MalnutritionClinics in Gastroenterology, Vol. 12, No. 2Immunochemical studies of molecular heterogeneity of cholecystokinin in duodenal perfusates and plasma in humans.Journal of Biological Chemistry, Vol. 258, No. 5Resorption von Triglyzeriden und fettlöslichen Vitaminen (außer Vitamin D)Pharmacology, Clinical Uses, and Adverse Effects of Ceruletide, A Cholecystokinetic Agent24 January 2012 | Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Vol. 2, No. 4Morton I. Grossman, M.D. Ph.D.: An Oral HistoryGastroenterology, Vol. 83, No. 1Effects of CCK on gastrointestinal function in lean and obese Zucker ratsPeptides, Vol. 3, No. 4Chemistry of the Gastrointestinal Hormones and Hormone-like Peptides and a Sketch of Their Physiology and PharmacologyEffects of truncal vagotomy and antrectomy on bombesin-stimulated pancreatic secretion, release of gastrin, and pancreatic polypeptide in the anesthetized dogDigestive Diseases and Sciences, Vol. 26, No. 10Effect of acetylcholine, gastrin, and glucagon alone and in combination with secretin and cholecystokinin on the secretion of the isolated perfused rat pancreasResearch in Experimental Medicine, Vol. 179, No. 3Serum insulin, glucose and triglyceride responses of Zucker obese and lean rats to cholecystokininPhysiology & Behavior, Vol. 26, No. 6Secretory effects of cholecystokinins on the isolated perfused porcine pancreasActa Physiologica Scandinavica, Vol. 111, No. 3Effect of Pentagastrin, Secretin, and Cholecystokinin on Gastric Secretion of Pepsin in Man22 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 16, No. 2Non-parallel secretion of pancreatic enzymes in sheep following hormonal or vagal stimulationComparative Biochemistry and Physiology Part A: Physiology, Vol. 68, No. 3Comparison of the effect of caerulein and testmeal on exocrine pancreatic secretion in the dogVeterinary Science Communications, Vol. 4, No. 1Feeding and drinking behavior responses of adult Zucker obese rats to cholecystokininPhysiology & Behavior, Vol. 25, No. 4The Effect of Acetaldehyde on Pancreatic and Gastric Secretion23 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 15, No. 7CholecystokininClinics in Gastroenterology, Vol. 9, No. 3Secretory effects of gastrins on isolated perfused porcine pancreasS. L. Jensen, J. F. Rehfeld, J. J. Holst, J. Fahrenkrug, O. V. Nielsen, and O. B. Schaffalitzky de Muckadell1 February 1980 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 238, No. 2Effect of Ninety-five Percent Pure Cholecystokinin on Gastrin-Stimulated Acid Secretion in Man and DogGastroenterology, Vol. 77, No. 1Interaction between gastrin, CCK, and secretin on canine antral smooth muscle in vitro.J W Fara, M Praissman, and J M Berkowitz1 January 1979 | American Journal of Physiology-Endocrinology and Metabolism, Vol. 236, No. 1Transport Processes in the Exocrine PancreasFluid secretion in the duodenum and intestinal handling of water and electrolytes in Zollinger-Ellison syndromeThe American Journal of Digestive Diseases, Vol. 23, No. 12The Interaction of Caerulein with the Rat Pancreas. 3. Structural Requirements for in vitro Binding of Caerulein-Like Peptides and Its Relationship to Increased Calcium Outflux, Adenylate Cyclase Activation, and SecretionEuropean Journal of Biochemistry, Vol. 91, No. 1Interactions of Cholecystokinin (CCK-PZ) and Gastrin on Motor Activity of Isolated Guinea-pig Antrum and Fundus23 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 13, No. 7Neurohormonal control of pancreatic secretionGastroenterology, Vol. 74, No. 2Satiety elicited by cholecystokinin in intact and vagotomized ratsPhysiology & Behavior, Vol. 19, No. 6In Vitro Effects of Gastrin on the Movement of Electrolytes across the Human Colon23 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 12, No. 8Plasma secretin concentration in man: effect of intraduodenal glucose, fat, amino acids, ethanol, HCI, or ingestion of a mealEuropean Journal of Clinical Investigation, Vol. 7, No. 3Plasma Secretin Concentration in Anaesthetized Pigs after Intraduodenal Glucose, Fat, Aminoacids, or Meals with Various pH23 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 12, No. 3The clinical application of exocrine pancreatic function testsDisease-a-Month, Vol. 22, No. 12The Influence of Hypercalcemia on Basal and Cholecystokinin-Stimulated Pancreatic, Gallbladder, and Gastric Functions in ManGastroenterology, Vol. 71, No. 3Effect of Gastrin on Pancreatic Enzyme Secretion and Gallbladder Emptying in ManGastroenterology, Vol. 71, No. 3Secretin, Cholecystokinin and Newer Gastrointestinal HormonesNew England Journal of Medicine, Vol. 294, No. 20Physiologie des exokrinen PankreasEffect of Cholecystokinin and 16,16-Dimethyl Prostaglandin E2 on RNA and DNA of Gastric and Duodenal MucosaGastroenterology, Vol. 70, No. 1Excitation of acid and pepsin secretion by cholecystokinin-pancreozymin in Pavlov and Heidenhain pouches of the ratExperientia, Vol. 31, No. 7Synthesis and Secretion of Protein and Pepsinogen by Rabbit Gastric Mucosa in Organ CultureGastroenterology, Vol. 69, No. 1Mode of action of the saline purgativesAmerican Heart Journal, Vol. 89, No. 6Effect of Hormones on Pancreatic Macromolecular TransportGastroenterology, Vol. 68, No. 6Gastrin-related compounds and their effect on gastric-acid and gastrin output in the dogJournal of Surgical Research, Vol. 18, No. 5Intestinal Phase of Gastric Acid Secretion: Augmentation of Maximal Response of Heidenhain Pouch to Gastrin and HistamineGastroenterology, Vol. 68, No. 4Effects of Intraduodenal Amino Acids, Fatty Acids, and Sugars on Secretin ConcentrationsGastroenterology, Vol. 68, No. 4GastrinCandidate Hormones of the GutGastroenterology, Vol. 67, No. 4The Neuroendocrine Design of the GutGastroenterology, Vol. 67, No. 1UPPER GASTROINTESTINAL HORMONES *1 June 1974 | Medical Journal of Australia, Vol. 1, No. 25Gastric Acid Does Drive Pancreatic Bicarbonate Secretion16 October 2020 | Scandinavian Journal of Gastroenterology, Vol. 9, No. 3Verhalten von Serumgastrin nach intraduodenaler Gabe von GalleVasoactive intestinal peptide: Secretin-like action on the avian pancreasExperientia, Vol. 29, No. 12SALINE PURGATIVES ACT BY RELEASING CHOLECYSTOKININThe Lancet, Vol. 302, No. 7822Effect of Pentagastrin on Canine Bile FlowGastroenterology, Vol. 64, No. 4The neurohumoral control of pancreatic exocrine secretionThe American Journal of Clinical Nutrition, Vol. 26, No. 3ACTIVE POLYPEPTIDES OF THE AMPHIBIAN SKIN AND THEIR SYNTHETIC ANALOGUESGastrointestinal Actions of the C-Terminal Tripeptide of GastrinGastroenterology, Vol. 63, No. 5Inhibitory action of alcohol on human exocrine pancreatic secretionThe American Journal of Digestive Diseases, Vol. 17, No. 10Augmentation of secretin-induced pancreatic secretion by caeruleinThe American Journal of Digestive Diseases, Vol. 17, No. 7Effects of Secretin, Cholecystokinin and Caerulein on Gastric Secretion in Response to Sham Feeding in DogsActa Physiologica Scandinavica, Vol. 85, No. 1Influence of Secretin and Cholecystokinin on Canine Gastric Secretion Elicited by Food and by Exogenous GastrinActa Physiologica Scandinavica, Vol. 85, No. 1Effect of Fat in the Duodenum on Gastric Acid Secretion in CatsGastroenterology, Vol. 62, No. 3Comparison of the effect of several gastrin-related compounds on acid secretion in dogsThe American Journal of Surgery, Vol. 123, No. 2Secretin: A Long Progress NoteGastroenterology, Vol. 62, No. 2Acetylcholine-releasing effect of gastrin and related polypeptidesEuropean Journal of Pharmacology, Vol. 17, No. 1Effect of Tetragastrin, Caerulein and Pancreozymin on the Enzyme Secretion of the Rabbit Pancreas in Vitro and in VivoJapanese Journal of Pharmacology, Vol. 22, No. 5Mechanism of the Inhibitory Action of Endogenous Cholecystokinin and Caerulein on Pentagastrin — Induced Gastric Secretion23 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 7, No. 7Effect of Jejunal Amino Acid Perfusion and Exogenous Cholecystokinin on the Exocrine Pancreatic and Biliary Secretions in ManGastroenterology, Vol. 61, No. 5Effect of Pentagastrin on Pancreatic Secretion in Man25 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 6, No. 6Effect of Cholecystokinin on Histamine- and Pentagastrin-Stimulated Acid Secretion in Conscious Cats25 February 2010 | Scandinavian Journal of Gastroenterology, Vol. 6, No. 5Effect of Cholecystokinin and Caerulein on Gastric Secretion in CatsGastroenterology, Vol. 60, No. 4Pepsinogens, Pepsins, and Pepsin InhibitorsGastroenterology, Vol. 60, No. 4Intestinal Hormones as Inhibitors of Gastric SecretionGastroenterology, Vol. 60, No. 1Chapter 8. Agents Affecting Gastrointestinal FunctionsAction of Caerulein on Gastric Secretion in ManGastroenterology, Vol. 59, No. 5Postprandial pH and Neutralizing Capacity of the Proximal Duodenum in DogsGastroenterology, Vol. 59, No. 1Action of caerulein on pancreatic secretion in manPharmacological Research Communications, Vol. 2, No. 2GASTRIN, CHOLECYSTOKININ, AND SECRETIN ACT ON ONE RECEPTORThe Lancet, Vol. 295, No. 7656Inhibition of Gastric Acid Secretion in Man by Peptide Analogues of CholecystokininNew England Journal of Medicine, Vol. 282, No. 10Effect of Sulfation on the Gastrointestinal Actions of CaeruleinGastroenterology, Vol. 58, No. 2Gastric and Pancreatic Secretion in Response to Gastric Distention in DogsGastroenterology, Vol. 57, No. 3 More from this issue > Volume 217Issue 1July 1969Pages 262-266 Copyright & PermissionsCopyright © 1969 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1969.217.1.262PubMed4891704History Published online 1 July 1969 Published in print 1 July 1969 Metrics