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Prospective Randomized Trial of Warfarin and Intermittent Pneumatic Leg Compression as Prophylaxis for Postoperative Deep Venous Thrombosis in Major Urological Surgery

1992; Lippincott Williams & Wilkins; Volume: 147; Issue: 4 Linguagem: Inglês

10.1016/s0022-5347(17)37467-0

1527-3792

Paramjit S. Chandhoke, Gretchen A. W. Gooding, Perinchery Narayan,

Central Venous Catheters and Hemodialysis

No AccessJournal of Urology1 Apr 1992Prospective Randomized Trial of Warfarin and Intermittent Pneumatic Leg Compression as Prophylaxis for Postoperative Deep Venous Thrombosis in Major Urological Surgery Paramjit S. Chandhoke, Gretchen A.W. Gooding, and Perinchery Narayan Paramjit S. ChandhokeParamjit S. Chandhoke , Gretchen A.W. GoodingGretchen A.W. Gooding , and Perinchery NarayanPerinchery Narayan View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)37467-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Postoperative deep venous thrombosis and pulmonary embolus remain a major source of morbidity and mortality for the urological surgery patient. We report the results of the first 100 patients in a prospective, randomized trial of low dose warfarin and intermittent pneumatic leg compression for deep venous thrombosis prophylaxis. All patients underwent preoperative and postoperative realtime ultrasound imaging and Doppler flow studies of the popliteal, femoral and iliac veins for the evaluation of deep venous thrombosis. Our results indicate that low dose warfarin is as effective as intermittent pneumatic leg compression for prophylaxis of deep venous thrombosis. Low dose warfarin can be used effectively without any significant bleeding complications. We recommend the use of low dose warfarin as an alternative to intermittent pneumatic leg compression for deep venous thrombosis prophylaxis of the urological patient undergoing a major urological operation. © 1992 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byClément C, Rossi P, Aissi K, Barthelemy P, Guibert N, Auquier P, Ragni E, Rossi D, Frances Y and Bastide C (2011) Incidence, Risk Profile and Morphological Pattern of Lower Extremity Venous Thromboembolism After Urological Cancer SurgeryJournal of Urology, VOL. 186, NO. 6, (2293-2297), Online publication date: 1-Dec-2011.Kibel A, Creager M, Goldhaber S, Richie J and Loughlin K (2018) LATE VENOUS THROMBOEMBOLIC DISEASE AFTER RADICAL PROSTATECTOMY: EFFECT OF RISK FACTORS, WARFARIN AND EARLY DISCHARGEJournal of Urology, VOL. 158, NO. 6, (2211-2215), Online publication date: 1-Dec-1997.Sieber P, Rommel M, Agusta V, Breslin J, Harpster L, Huffnagle H and Stahl C (2018) Is Heparin Contraindicated in Pelvic Lymphadenectomy and Radical Prostatectomy?Journal of Urology, VOL. 158, NO. 3, (869-871), Online publication date: 1-Sep-1997.Soderdahl D, Henderson S and Hansberry K (2018) A Comparison of Intermittent Pneumatic Compression of the Calf and Whole Leg in Preventing Deep Venous Thrombosis in Urological SurgeryJournal of Urology, VOL. 157, NO. 5, (1774-1776), Online publication date: 1-May-1997.Kibel A and Loughlin K (2018) Pathogenesis and Prophylaxis of Postoperative Thromboembolic Disease in Urological Pelvic SurgeryJournal of Urology, VOL. 153, NO. 6, (1763-1774), Online publication date: 1-Jun-1995. Volume 147Issue 4April 1992Page: 1056-1059 Advertisement Copyright & Permissions© 1992 by The American Urological Association Education and Research, Inc.Keywordsultrasonic diagnosisthrombophlebitiswarfarinurologyMetricsAuthor Information Paramjit S. Chandhoke Dornier/American Foundation for Urologie Disease Scholar. Present address: Division of Urologie Surgery, Washington University School of Medicine, 4960 Audubon Ave., St. Louis, Missouri 63110. More articles by this author Gretchen A.W. Gooding More articles by this author Perinchery Narayan More articles by this author Expand All Advertisement PDF downloadLoading ...