A Light- and Electron-Microscopic Study of a Case of Multiple Eccrine Spiradenoma**From the Armed Forces Institute of Pathology and the Dermatology Service, Walter Reed General Hospital, Washington 25, D.C.
1962; Elsevier BV; Volume: 38; Issue: 5 Linguagem: Inglês
10.1038/jid.1962.52
ISSN1523-1747
AutoresBryce L. Munger, Bronson M. Berghorn, Elson B. Helwig,
Tópico(s)Caveolin-1 and cellular processes
ResumoThe eccrine spiradenoma is a benign neoplasm of skin first described by Kersting and Helwig (11) in 1956. They considered the lesion a derivative of the eccrine sweat gland and described a characteristic clinical and histopathologic picture. Clinically, spontaneous episodes of paroxysmal pain are associated with the tumor; and histopathologically, the encapsulated nodules of tumor are composed of masses of basophilic cells, usually arranged in whorls, cords, and pseudo-glands. Within the whorls and pseudoglands two types of cells are noted: peripheral intensely staining cells and central pale-staining cells. Kersting and Helwig (11) considered the possibility that these two cells might correspond to the cell types of the secretory segment of eccrine sweat glands.
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