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BIBTEX RIS

Essential Oil from the Leaves of Annona vepretorum : Chemical Composition and Bioactivity

2012; SAGE Publishing; Volume: 7; Issue: 2 Linguagem: Inglês

10.1177/1934578x1200700240

ISSN

1934-578X

Autores

Emmanoel Vilaça Costa, Lívia Macedo Dutra, Paulo César de Lima Nogueira, Valéria Regina de Souza Moraes, Marcos José Salvador, Luis Henrique Gonzaga Ribeiro, Fernanda Ramos Gadelha,

Tópico(s)

Insect Pest Control Strategies

Resumo

The essential oil from the leaves of Annona vepretorun was obtained by hydrodistillation using a Clevenger-type apparatus and analyzed by GC-MS and GC-FID. Eighteen compounds representing 98.1% of the crude essential oil were identified. The major compounds identified were bicyclogermacrene (43.7%), spathulenol (11.4%), alpha-felandrene (10.0%), alpha-pinene (7.1%), (E)-beta-ocimene (6.8%), germacrene D (5.8%), and p-cymene (4.2%). The trypanocidal activity against Trypanosoma cruzi epimastigote forms, as well as, the antimicrobial and antioxidant proprieties was investigated. The essential oil showed a potent trypanocidal activity with IC50 value of 31.9 +/-1.3 microg x mL(-1). For antimicrobial activity, the best result was observed against Candida tropicalis with a MIC value of 100 microg x mL(-1). For antioxidant capacity the essential oil showed weak activity.

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