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Pituitary Disorders During Pregnancy

1995; Elsevier BV; Volume: 24; Issue: 1 Linguagem: Inglês

10.1016/s0889-8529(18)30051-3

1558-4410

Diane Prager, Glenn D. Braunstein,

Growth Hormone and Insulin-like Growth Factors

Hormonal changes during pregnancy include an increase in prolactin secretion and decreases in gonadotropins and growth hormone. Enlargement of pituitary tumors, especially prolactin-secreting macroadenomas, may occur rarely and may require bromocryptine treatment, surgical treatment, or both. Hypopituitarism is usually the result of antepartum or postpartum hemorrhage or lymphocytic hypophysitis. A pregnancy-specific form of diabetes insipidus that is treated with dDAVP, an analogue that is resistant to placental vasopressinase, may occur.