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PROCEEDINGS OF THE JOINT MEETING BETWEEN THE SCANDINAVIAN AND BRITISH PHARMACOLOGICAL SOCIETIES

1968; Wiley; Volume: 34; Issue: 1 Linguagem: Inglês

10.1111/j.1476-5381.1968.tb07962.x

1476-5381

A I Pekkarinen,

Drug Transport and Resistance Mechanisms

British Journal of PharmacologyVolume 34, Issue 1 p. 189P-238P Free Access PROCEEDINGS OF THE JOINT MEETING BETWEEN THE SCANDINAVIAN AND BRITISH PHARMACOLOGICAL SOCIETIES First published: September 1968 https://doi.org/10.1111/j.1476-5381.1968.tb07962.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat REFERENCES ÄNggård, E. & Samuelsson, B. (1966). Purification and properties of a 15-hydroxy-prostaglandin dehydrogenase from swine lung. Arkiv Kemi. 25, 293– 300. Lowry, O. H., Passoneau, Janet V., Schultz, D. W. & Rock, Martha (1961). The measurement of pyridine nucleotides by enzymatic cycling. J. biol. Chem., 236, 2746– 2755. REFERENCES Burchall, J. J. & Hitchings, G. H. (1965). Inhibitor binding analysis of dihydrofolate reductases from various species. Molec. Pharmac., 1, 126– 136. Jaffe, J. J. & McCormack, Jr., J. J. (1967). Dihydrofolate reductase from Trypanosoma equiperdum. 1. Isolation, partial purification, and properties. Molec. Pharmac., 3, 359– 369. REFERENCES Dean, C. R., Hollenberg, M. D. & Hope, D. B. (1967). The relationship between neurophysin and the soluble proteins of pituitary neurosecretory granules. Biochem. J., 104, 8C– 10C.. Dean, C. R. & Hope, D. B. (1967). The isolation of purified neurosecretory granules from bovine pituitary posterior lobes. Biochem. J., 104, 1082– 1088. Dean, C. R. & Hope, D. B. (1968). The isolation of neurophysin-I and -II from bovine pituitary neurosecretory granules separated on a large scale from other subcellular organelles. Biochem. J., 106, 565– 573. Hollenberg, M. D. & Hope, D. B. (1968). The isolation of the native hormone-binding proteins from bovine pituitary posterior lobes. Biochem. J., 106, 557– 564. La Bella, F. S., Reiffenstein, R. J. & Beaulieu, G. (1963). Subcellular fractionation of bovine posterior pituitary glands by centrifugation. Arch. Biochem. Biophys., 100, 399– 408. REFERENCES Dean, C. R., Hollenberg, M. D. & Hope, D. B. (1967). The relationship between neurophysin and the soluble proteins of pituitary neurosecretory granules. Biochem. J., 194, 8C-– 10C.. Dean, C. R. & Hope, D. B. (1968). The isolation of neurophysin-I and -II from bovine pituitary neurosecretory granules separated on a large scale from other subcellular organelles. Biochem. J., 106, 565– 573. Dean, C. R., Hope, D. B. & Kažić, T. (1968). Evidence for the storage of oxytocin with neurophysin-I and of vasopressin with neurophysin-II in separate neurosecretory granules. (This meeting.). Ferguson, K. A. & Wallace, A. L. C. (1961). Starch gel electrophoresis of anterior pituitary hormones. Nature, Lond., 190, 629– 630. Hollenberg, M. D. & Hope, D. B. (1968). The isolation of the native hormone-binding proteins from bovine pituitary posterior lobes. Biochem. J., 106, 557– 564. REFERENCES Uvnäs, B. & Thon, I. L. (1961). Evidence for enzymatic histamine release from isolated rat mast cells. Expl Cell Res., 23, 45– 57. REFERENCES Norn, S. (1965). Influence of antirheumatic agents on the release of histamine from rat peritoneal mast cells after an antigen—antibody reaction. Acta pharmac. tox., 22, 369– 378. Norn, S. (1967). Release of histamine from sensitized rat peritoneal cells by specific and unspecific antigens. Acta pharmac. tox., 25, 456– 460. REFERENCES Bieck, P., Stock, K. & Westermann, E. (1967). Über die Bedeutung des Serotonins im Fettgewebe. Arch. Pharmak. exp. Path., 256, 218– 236. Mellander, S. (1960). Comparative studies on the adrenergic neurohumoral control of resistance and capacitance blood vessels in the cat. Acta physiol. scand., 50, suppl. 176, 1– 86. Rosell, S. (1966). Release of free fatty acids from subcutaneous adipose tissue during sympathetic nerve stimulation. Acta physiol. scand., 67, 343– 351. REFERENCES Beviz, A. & Lundholm, L. (1968). Life Sci., in the press. Beviz, A. & Mohme-Lundholm, E. (1967). The effect of noradrenaline on the intermediary metabolism of brown adipose tissue. Acta pharmac. Kbh., 25, suppl. 4, 21– 22. Sutherland, E. W., Robinson, G. A. & Butcher, R. W. (1968). Some aspects of the biological role of adenosine 3′,5′-monophosphate (cyclic AMP). Circulation, 37, 279– 306. REFERENCES Hermansen, K. (1968). Some pharmacological properties of a new β-adrenergic blocking agent, 1-(isopropylamino)-3-(o-phenoxyphenoxy)-2-propanol, HCl (Ph QA 33). Acta pharmac. tox., in the press. Somani, P. & Lum, B. K. B. (1965). The anti-arrhythmic actions of beta adrenergic blocking agents. J. Pharmac. exp. Ther., 147, 194– 204. REFERENCES Clark, D. E. & Leach, G. D. H. (1968). The influence of bretylium on the interactions of infused sympathomimetic amines and tyramine in the reserpine-treated pithed rat. Br. J. Pharmac. Chemother., 32, 392– 401. Kayaalp, S. O. & Kiran, B. K. (1966). Mechanism of a sympathomimetic action of propranolol in dog. Br. J. Pharmac. Chemother., 28, 15– 22. Kayaalp, S. O. & Turker, R. K. (1967). Further observations on the pressor action of propranolol. Br. J. Pharmac. Chemother., 30, 668– 675. Shipley, R. E. & Tilden, J. J. (1947). Pithed rat preparation suitable for assaying pressor substances. Proc. Soc. exp. Biol. Med., 64, 453– 455. REFERENCES Champlain, J., Krakoff, L. H. & Axelrod, J. (1966). A reduction in the accumulation of H3-norepinephrine in experimental hypertension. Life Sci., Oxford, 5, 2283– 2291. Doyle, A. E. & Frazer, J. R. E. (1961). Vascular reactivity in hypertension. Circulation Res., 9, 755– 761. Gitlow, S. E., Wilk, E. K., Wolf, R. L. & Nafthi, N. F. (1964). Plasma clearance of d,1-β-H3-norepinephrine in normal subjects and patients with essential hypertension. J. clin. Invest., 43, 2009– 2015. Jones, A. W., Peterson, L. H. & Feigel, E. O. (1967). Vascular alterations in experimental hypertension. In Baroreceptors and Hypertension, ed. P. Kezdi Oxford: Pergamon Press. Kezdi, P. (1967). Resetting of the carotid sinus in experimental renal hypertension. In Baroreceptors and Hypertension, ed. P. Kezdi Oxford: Pergamon Press. McCubbin, J. W., Green, J. H. & Page, I. H. (1956). Baroreceptor function in chronic renal hypertension. Circulation Res., 4, 205– 210. McCubbin, J. W. & Page, I. H. (1963). Renal pressor system and neurogenic control of arterial pressure. Circulation Res., 12, 553– 559. REFERENCES Bacq, Z. M. (1965). Chemical Protection against Ionizing Radiation. U.S.A.: Springfield, C. Thomas. Bacq, Z. M. & Goutier, R. (1968). Mechanisms of action of sulfur containing radioprotectors. Brook-haven symposium on Recovery from Radiation Injury, June 1967, in the press. Baugnet-Mahieu, L., Goutier, R. & Semal, M. (1967). Effects of total-body irradiation and AET on the activity of thymidine-phosphorylating kinases during liver regeneration. Radiat. Res., 31, 808– 825. Beaumariage, M. L., Van Caneghem, P. & Bacq, Z. M. (1966). Étude de certaines propriétés pharma-codynamiques de la cystamine et de la cystéamine chez diverses espèces animales. Strahlentherapie, 131, 342– 351. Firket, H. & Lelièvre, P. (1966). Effet de la cystamine sur la respiration, la phosphorylation oxydative de l'ufrastructure des mitochondries du rat. Int. J. rad. Biol., 10, 403– 415. Hugon, J., Maisin, J. R. & Borgers, M. (1966). Modifications ultrastructurales après radioprotecteurs. Int. J. rad. Biol., 11, 105– 116. Lecomte, J., Cession-Fossion, A., Libon, J. C. & Bacq, Z. M. (1964). Sur quelques effets pharmaco-dynamiques généraux de la cystamine chez le rat. Archs int. Pharmacodyn. Thér., 148, 487– 510. Lecomte, J. & Bacq, Z. M. (1965). Propriétés vasomotrices de la 2-mercaptoethylguanidine (MEG) chez le rat. Archs int. Pharmacodyn. Thér., 158, 480– 497. Plomteux, G., Beaumariage, M. L., Bacq, Z. M. & Heusghem, C. (1967). Variations enzymatiques dans le plasma du rat après injection d'une dose radioprotectrice de cystéamine. Biochem. Pharmac., 16, 1601– 1607. Plomteux, G., Beaumariage, M. L., Bacq, Z. M. & Heusghem, C. (1968). Influence du β-mercapto-ethanol sur certains enzymes plasmatiques du rat. Biochem. Pharmac., in the press. Van Caneghem, P. & Stein, F. (1967). Influence de l'injection de cystamine et de divers états de choc sur les protéines plasmatiques du rat, du lapin et du poulet. Archs int. Physiol. Biochem., 75, 769– 786. REFERENCES Ahlquist, R. P. & Levy, B. (1959). Adrenergic receptive mechanism of canine ileum. J. Pharmac. exp. Ther., 127, 146– 149. Jenkinson, D. H. & Morton, J. K. (1965). Effects of noradrenaline and isoprenaline on the permeability of depolarized intestinal smooth muscle to inorganic ions. Nature, Lond., 205, 505– 506. REFERENCES Bartlet, A. L. & Hassan, T. (1968a). Some actions of histamine and 5-hydroxytryptamine on isolated chicken oesophagus. Br. J. Pharmac. Chemother., 32, 156– 163. Bartlet, A. L. & Hassan, T. (1968b). The action of physostigmine and the distribution of cholinesterases in the chicken oesophagus. Br. J. Pharmac. Chemother., in the Press. Hassan, T. (1967). Effects of stimulation of the cervical vagus and descending oesophageal nerves on the alimentary tract of the domestic fowl. Zentbl. Vet Med. A., 14, 854– 861. REFERENCES Ansary, H. R. (1965). Investigation of the role of ovaries in the mechanism of action of reserpine on the genital system of rat. M.Sc. thesis, University of Karachi, Pakistan. Khan, I. & Qureshi, Z. (1967). Effects of reserpine on the sensitivity of rat isolated uterine preparations to oxytocic drugs. J. Pharm. Pharmac., 19, 815. Khan, I. & Shariff, S. H. (1967). Investigation into the effects of reserpine on isolated uterine preparation of hypophysectomized female rats. Life Sci., 6, 2469. REFERENCES Eckenhoff, J. E. & Oech, S. R. (1960). The effects of narcotics and antagonists upon respiration and circulation in man. Clin. Pharm. Ther., 1, 483– 524. Evans, A. G. J., Nasmyth, P. A. & Stewart, H. C. (1952). The fall of blood pressure caused by intravenous morphine in the rat and the cat. Br. J. Pharmac. Chemother., 7, 542– 552. Feldberg, W. & Paton, W. D. M. (1951). Release of histamine from skin and muscle in the cat by opium alkaloids and other histamine liberators. J. Physiol., Lond., 114, 490– 509. Gyermek, L. (1961). 5-Hydroxytryptamine antagonists. Pharmac. Rev., 13, 399– 439. Schmidt, C. F. & Livingston, A. E. (1933). The action of morphine on the mammalian circulation. J. Pharmac. exp. Ther., 47, 411– 441. REFERENCES Brodie, B. B., Burns, J. J., Mark, L. C., Lief, P. A., Bernstein, E. & Papper, M. (1953). The fate of pentobarbital in man and dog and a method for its estimation in biological material. J. Pharmac. exp. Ther., 109, 26. Sotaniemi, E. (1967). The influence of environmental temperature on the concentration of pentobarbital and barbital in the liver and brain. An experimental study on guinea pigs. Acta Pharmac. Tox., 25, suppl. 5. REFERENCES Eränkö, O., Koelle, G. B. & Räisänen, Liisa (1967). J. Histochem. Cytochem., 15, 674– 679. Jensen-Holm, J. (1965). A titrimetric method for separate determination of specific and non-specific Cholinesterase activity in the absence and presence of irreversible inhibitors (paroxan and DFP). J. Pharmac., Kbh., 23, 73– 84. Jensen-Holm, J. (1967). Cholinesterase and protein changes in sympathetic ganglia after guanethidine. Acta pharmac., Kbh., 25, suppl. 4, 74. Jensen-Holm, J. & Zaimis, Eleanor (1967). Heart rate and Cholinesterase changes produced by guanethidine and reserpine. Br. J. Pharmac. Chemother., 30, 3 (title only). REFERENCES Corne, S. J. & Stephens, R. J. (1966). Peri-arterial and extradural devices for measuring changes of blood pressure and intracranial pressure in conscious animals. J. Physiol., Lond., 188, 9– 10P.. Stephens, R. J. & Corne, S. J. (1966). The measurement of changes of blood pressure and intracranial pressure in conscious laboratory animals. Br. J. Pharmac. Chemother., 27, 443 (title only). REFERENCES Bennet-Clark, H. C. & Evans, C. R. (1963). Fragmentation of patterned targets when viewed as prolonged after-images. Nature, Lond., 199, 1215– 1216. Evans, C. R. (1965). Some studies of pattern perception using a stabilized retinal image. Br. J. Psychol., 56, 121– 133. REFERENCES Ross, R. B. & Russell, I. S. (1964). Lateralization and one-trial interhemispheric transfer of avoidance conditioning. Nature, Lond., 204, 909– 910. REFERENCES Feldberg, W. & Myers, R. D. (1964). Effects on temperature of amines injected into the cerebral ventricles. A new concept of temperature regulation. J. Physiol., Lond., 174, 226– 237. REFERENCES Axelrod, J., Whitby, L. G. & Hertting, G. (1961). Effect of psychotropic drugs on the uptake of H3-norepinephrine by tissues. Science, N.Y., 133, 383– 384. Cairncross, K. D., Gershon, S. & Gust, I. D. (1963). Some aspects on the mode of action of imipramine. J. Neuropsychiat., 4, 224– 231. Glowinski, J. & Axelrod, J. (1964). Inhibition of uptake of tritiated-noradrenaline in the intact rat brain by imipramine and structurally related compounds. Nature, Lond., 204, 1318– 1319. Sigg, E. B. (1961). Pharmacological studies with tofranil. Canad. Psychiatric. Assoc. J., 4, S75– 83. Vernier, V. G. (1961). The pharmacology of antidepressant agents. Dis. nerv. Syst., 22, 7– 13. REFERENCES Arnfred, T. & Randrup, A. (1968). Cholinergic mechanism in brain inhibiting amphetamine induced stereotyped behaviour. Acta pharmac. tox., in the Press. Randrup, A., Munkvad, I. & Udsen, P. (1963). Adrenergic mechanisms and amphetamine induced abnormal behaviour. Acta pharmac. tox., 20, 145– 157. Schiørring, E. & Randrup, A. (1968). “Paradoxical” stereotyped activity of reserpinized rats. Int. J. Neuropharmac., 7, 71– 73. REFERENCES Wahlström, G. (1964). The circadian rhythm in the canary studied by self-selection of light and darkness. Acta Soc. Med, upsal., 69, 241– 271. REFERENCES Ernst, A. M. (1967). Mode of action of apomorphine and dexamphetamine on gnawing compulsion in rats. Psychopharmacologia, 10, 316– 323. Pedersen, V. (1967). Potentiation of apomorphine effect (compulsive gnawing behaviour) in mice. Acta pharmac. tox., 25, suppl. 4, 63. Ther, L. & Sohramm, H. (1962). Apomorphin-synergismus (Zwangsnegen bei Mäusen) als Test zur Differenzierung psychotroper Substanzen. Archs. int. Pharmacodyn. Thér., 138, 302– 310. REFERENCES Carlsson, A. & Lindqvist, M. (1963). Effect of chlorpromazine or haloperidol on formation of 3-m ethoxy tyramine and normetanephrine in mouse brain. Acta pharmac. Kbh., 20, 140– 144. Carlsson, A. & Waldeck, B. (1964). Method for the fluorimetric determination of 3-methoxytyramine in tissues and the occurrence of this amine in brain. Scand. J. clin. lab. Invest., 16, 133– 138. REFERENCES Burkard, W. P., Gey, K. F. & Pletscher, A. (1967). Activation of tyrosine hydroxylation in rat brain in vivo by chlorpromazine. Nature, Lond., 213, 732– 733. Carlsson, A. & Lindqvist, M. (1963). Effect of chlorpromazine and haloperidol on formation of 3-methoxytyramine and normetanephrine in mouse brain. Acta pharmac. tox., 20, 140– 144. Neff, N. H. & Costa, E. (1966). Effect of tricyclic antidepressants and chlorpromazine on brain catecholamine synthesis. In Proceedings of the First Symposium on Antidepressant Drugs, ed. S. Garattini & M. N. G. Dukes Milan: Int. Congress series No. 122, Excerpta Medica Foundation. Sedvall, G., Weise, W. K. & Kopin, I. J. (1968). The rate of norepinephrine synthesis measured in vivo during short intervals; influence of adrenergic nerve impulse activity. J. Pharmac., exp. Ther., 159, 274– 282. Udenfriend, S. & Zaltzman-Nirenberg, P. (1963). Norepinephrine and 3,4-dihydroxy-phenylethylamine turnover in guinea pig brain in vivo. Science, 142, 394– 396. REFERENCES Krnjević, K. & Phillis, J. W. (1963). Actions of certain amines on cerebral cortical neurones. Br. J. Pharmac. Chemother., 20, 471– 490. Roberts, M. H. T. & Straughan, D. W. (1968). Actions of noradrenaline and mescaline on cortical neurones. Naunyn-Schmiedeberg's Arch. Pharmak. exp. Path., 259, 191. REFERENCES Eisenfeld, A. J., Axelrod, J. & Krakoff, L. (1967). Inhibition of the extraneuronal accumulation and metabolism of norepinephrine by adrenergic blocking agents. J. Pharmac. exp. Ther., 156, 107– 113. Langer, S. Z., (1968). J. Physiol., Lond., in the Press. REFERENCES Laverty, R., Sharman, D. F. & Vogt, M. (1965). Action of 2,4,5-trihydroxyphenylethylamine on the storage and release of noradrenaline. Br. J. Pharmac. Chemother., 24, 549. Porter, C. C., Totaro, J. A. & Stone, C. A. (1963). Effect of 6-hydroxydopamine and some other components on the concentration of norepinephrine in the hearts of mice. J. Pharmac. exp. Ther., 140, 308. Thoenen, H., Hurlimann, A. & Haefely, W. (1968). Mechanisms of amphetamine accumulation in the isolated perfused heart of the rat. J. Pharm. Pharmac., 20, 1. von Tranzer, J. P. & Thoenen, H. (1967). Ultramorphologische Veränderungen der sympathischen Nervendigungen der Katze nach Vorbehandlung mit 5-und 6-Hydroxy-Dopamin, Arch. exp. Path. Pharmac., 257, 342. REFERENCES Kopin, I. J. (1966). Biochemical aspects of release of norepinephrine and other amines from sympathetic nerve endings. Pharmac. Rev., 18, 513– 523. Sandler, M. & Ruthven, C. R. J. (1966). 4-Hydroxy-3-methoxy-phenylglycol and other compounds in neuroblastoma. In Recent Results in Cancer Research. II. Neuroblastomas. Biochemical Studies, ed. C. Bohuon, pp. 55– 59. Berlin: Springer. Sandler, M. & Youdim, M. B. H. (1968). Promotion of 4-hydroxy-3-methoxyphenylglycol formation in man by reserpine. Nature, Lond., 217, 771– 772. Smith, C. B. (1966). The role of monoamine oxidase in the intraneuronal metabolism of norepinephrine released by indirectly acting sympathomimetic amines or by adrenergic nerve stimulation. J. Pharmac. exp. Ther., 151, 207– 220. REFERENCES Malmfors, T. (1967). Fluorescent histochemical studies on the uptake, storage and release of catecholamines. Circulation Res., 21, Suppl. 3, 25– 42. REFERENCES Corrodi, H. & Hanson, L. (1966). Central effects of inhibitor of tyrosine hydroxylase. Psychopharmacologia, 10, 116– 125. Obianwu, H. O. (1967). Sympathetic and receptor blockade after prenylamine (Segontin). Acta pharmac. tox., 25, 141– 154. REFERENCES Iversen, L. L. (1965). The uptake of catecholamines at high perfusion concentrations in the isolated rat heart: a novel catecholamine uptake process. Br. J. Pharmac. Chemother., 25, 18– 33. Malmfors, T. (1965). Studies on adrenergic nerves. Acta physiol. scand., 64, Suppl. 248, 1– 93. REFERENCES Manuilov, I. A. (1958). Sechenov Physiol. J. USSR (English Transi.), 44, 458. REFERENCES Daniel, E. E. & Robinson, K. (1960). The secretion of sodium and uptake of potassium by isolated uterine segments made sodium rich. J. Physiol., Lond., 154, 421– 444. Daniel, E. E. (1964). The interconnection between active transport and contracture in uterine tissues. Can. J. Physiol. Pharmac., 42, 453– 495. Ho, R. J., Jeanrenaud, B., Posternak, Th. & Renold, A. E. (1967). Insulin-like action of ouabain. Biochim. Biophys. Acta, 144, 74– 82. Sutherland, E. W. & Rall, T. W. (1957). The properties of an adenine ribonucleotide produced with cellular particles ATP, Mg++ and epinephrine or glucagon. J. Am. chem. Soc., 79, 3608. Sutherland, E. W., Rall, T. W. & Menon, T. (1962). Adenyl cyclase-distribution, preparation and properties. J. biol. Chem., 237, 1220– 1227. REFERENCES Clarkson, T. W. & Magos, L. (1967). The effect of sodium maleate on the renal deposition and excretion of mercury. Br. J. Pharmac. Chemother., 31, 560– 567. REFERENCES Day, M. D. & Rand, M. J. (1964). Some observations on the pharmacology of α-methyldopa. Br. J. Pharmac. Chemother., 22, 72– 86. Henning, M. (1967). Blood pressure and noradrenaline levels after treatment with α-methyldopa, α-methyldopamine and α-methyl-m-tyrosine. J. Pharm. Pharmac., 19, 775– 779. REFERENCES Rosell, Sune & Uvnas, Börje (1962). Vasomotor nerve activity and oxygen uptake in skeletal muscle of the anesthetized cat. Acta physiol. scand., 54, 209– 222. REFERENCES Gaddum, J. H. & Horton, E. W. (1959). The extraction of human urinary kinin (substance Z) and its relation to the plasma kinins. Br. J. Pharmac. Chemother., 14, 117– 124. Guth, P. S. (1959). Kinins produced from buvine collostrum by kallikrein and saliva. Br. J. Pharmac. Chemother., 14, 549– 552. Horton, E. W. (1958). Assay of kallikrein in urine. J. Physiol., Lond., 142, 36P.. Tella, A. & Maegraith, B. G. (1965). Physiopathological changes in primary acute blood transmitted malaria and Babesia infections. I—Observations on parasites and blood cells in rhesus monkeys, mice, rats, and puppies. Ann. trop. Med. Parasit., 59, 135. Tella, A. & Maegraith, B. G. (1966). Studies on bradykinin and bradykininogen in malaria. Ann. trop. Med. Parasit., 60, 304– 317. REFERENCES Fredholm, B. (1966). Studies on a mast cell degranulating factor in bee venom. Biochem. Pharmac., 15, 2037– 2043. REFERENCES Hansky, J. (1967). Calcium content of duodenal juice. Am. J. dig. Dis., 12, 725– 733. Rune, S. J. (1967). Individual variation in secretory capacity of gastric acid to stimulation with solid food and with histamine. Clin. Sci., 32, 443– 452. Volume34, Issue1September 1968Pages 189P-238P ReferencesRelatedInformation